Speciation and Antimicrobial Resistance Pattern of Acinetobacter Species From Clinical Isolates in Tertiary Care Hospital
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 6
Abstract
Introduction: Acinetobacter species are Gram negative non-fermentative bacteria. Previously these were considered just as an opportunistic pathogens, but recently have been emerged as an important nosocomial pathogen worldwide. In recent few years these have been involved in many outbreaks of hospital infections. Aims and Objectives: The present study was conducted to type the Acinetobacter isolates and to find the sensitivity and resistance pattern of Acinetobacter in our set up. Materials and Methods: The current study was conducted in our microbiology department, RIMS, Ranchi for a period of 1 year (January 2016 - December 2016). Different specimens were processed by standard methods and antibiotic sensitivity was performed by Kirby- Bauer disk diffusion technique as per Clinical and Laboratory Standards Institute (CLSI) guidelines. Results: Out of a total 1890 culture positive specimens, 110 (5.8%) Acinetobacter isolates were obtained from various specimens. Speciations were done in which predominance of A. baumannii (84.5%) was seen followed by A.lwoffii (7.26%); A. haemolyticus (4.5%) and A. junnii (3.63%). High level of resistance were seen for Ampicillin (79.1%); Cefotaxime (78.1%); Ceftazidime (73%); Ceftriaxone (70.9%) and for urine samples Nalidixic acid (70%) and Norfloxacin (70%). Significant level of resistance were observed for Ciprofloxacin (63.64%), Levofloxacin (52.73%), Doxycycline (60%), Trimethoprim-sulfamethoxazole (60%); Gentamycin (54.55%). Sensitivity to Carbapenems was 70.9% and to both Amikacin and Piperacillin- tazobactam, 63.66% were found. Conclusion: In recent few years due to emergence of multidrug resistant strains of Acinetobacter, situation has become more problematic for the clinicians. So clinical co-relation must be undertaken to exclude commensal contaminant, before considering it to be a pathogen and prescribing appropriate antibiotic to the patient.
Authors and Affiliations
Ashok Kumar Sharma, Khushboo Kumari, Manoj Kumar, Amber Prasad
Keywords
Related Articles
- EP ID EP533202
- DOI 10.21276/ijmrp.2018.4.6.029
- Views 84
- Downloads 0
Bacteriological Profile and Antibiogram of Burn Wound Infections from Burn Patients at RIMS, Ranchi
Introduction: Burn wounds are especially prone to infection which is a major cause of morbidity and mortality in hospitalised burn patients. Identification of bacterial isolates from specimens of burn patients and study...
A Study to Establish the DMFT Index amongst Adults Reporting to the Hospital
Background: Despite of various technological advances and the truth that it is a preventable condition, it continues to be a major health issue. According to World Health organisation, it is amongst the three most common...
The Magnitude and Predictors of Socially Concealed Behaviors (Violence) among Adolescents Visiting Primary Health Care Centers in Jeddah City, Kingdom of Saudi Arabia, Jeddah - 2017
Introduction: Studies illustrated that adolescents' neurological development as decision-making and future-oriented thinking is not fully developed, making them more vulnerable to several risky behaviors. Risky behaviors...
Assessment of Knowledge, Attitudes and Practices Toward Prevention of Hepatitis B Virus Infection Among Medical Students in Hail Region, Saudi Arabia
Objective: To assess the knowledge regarding symptoms, risk factors and prevention of hepatitis B virus infection among medical students in Hail, Saudi Arabia. Methods: A cross-sectional study was conducted at the facult...
Voiding Patterns In Pitcher Pot Ileal Neobladder
Objectives: A good long term functional outcome of any orthotopic bladder substitution will ultimately decide its utility. Therefore, we analyzed exclusively voiding patterns in patients with Pitcher Pot Ileal Neobladder...