Specific gene hypomethylation and cancer: new insights into coding region feature trends.

Journal Title: Bioinformation - Year 2009, Vol 3, Issue 8

Abstract

Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been performed. In this work, the inter-cancer coding region features comparative analysis carried out, show insights into what structural trends/patterns are present in the studied cancers.

Authors and Affiliations

Keywords

Related Articles

In silico Construction of phosphomannose isomerase (PMI) transformation vectors and evaluation of the effectiveness of vectors in tobacco (Nicotiana tabacum L.)

Phosphomannose isomerase (pmi) gene isolated from Escherichia coli allows transgenic plants carrying it to convert mannose-6-phosphate (from mannose), a carbon source that could not be naturally utilized by plants into f...

Phylogenetic analysis of chloroplast matK gene from Zingiberaceae for plant DNA barcoding.

MaturaseK gene (MatK) of chloroplast is highly conserved in plant systematics which is involved in Group II intron splicing. The size of the gene is 1500 bp in length, located with in the intron of trnK. In the present s...

Alternative splicing: a paradoxical qudo in eukaryotic genomes.

One of the most remarkable observations stemming from the sequencing of genomes of diverse species is that the number of protein-coding genes in an organism does not correlate with its overall cellular complexity. Altern...

Glaucoma database.

Glaucoma, a complex heterogenous disease, is the leading cause for optic nerve-related blindness worldwide. Primary open angle glaucoma (POAG) is the most common subset and by the year 2020 it is estimated that approxima...

Molecular modelling of the TSR domain of R-spondin 4.

R-spondin 4 is a secreted protein mainly associated with embryonic nail development. R-spondins have been recently identified as heparin-binding proteins with high affinity. Proteoglycan binding has been associated with...

Download PDF file
  • EP ID EP86359
  • DOI 10.6026/97320630003340
  • Views 111
  • Downloads 0

How To Cite

(2009). Specific gene hypomethylation and cancer: new insights into coding region feature trends.. Bioinformation, 3(8), 340-343. https://europub.co.uk/articles/-A-86359