Specific IgE Immunoassay for House Dust Mites by Using Multiple Allergen Simultaneous Test (MAST) in Asthmatic Children
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2017, Vol 68, Issue 1
Abstract
Background: house dust mites are considered as a major cause of bronchial asthma in young children. Inhalation of dust mite allergens by hypersensitive individuals can result in acute attacks of bronchial asthma. Multiple allergen simultaneous test (MAST) for the detection of specific IgE of different allergens is one of the important diagnostic tools for bronchial asthma. Patients and Methods: the study group consisted of forty children suffering from bronchial asthma selected from the outpatient clinic of Pediatrics, Faculty of Medicine, Al-Azhar University, New Damietta, Egypt as well as another normal forty healthy volunteer children were selected as controls. Total IgE immunoassay and quantitative measurement of allergen specific IgE (Biocheck GmbH, Germany) were estimated for all of them. Results: it was found that, out of 27 positive IgE subjects, 20 were positive by poly-check test providing sensitivity of 74.1%; and out of 53 negative IgE subjects, 50 were negative, providing specificity of 94.3%. Conclusion: Poly-check (MAST), in vitro tests can be used in screening for allergens in asthmatic children with high specificity.
Authors and Affiliations
Mohammed Youssef Saad1; Hany Abd El-Hady El-Khaleegy2
Keywords
Related Articles
- EP ID EP501224
- DOI -
- Views 126
- Downloads 0
Reliability and Validity of Field Testing of the World Health Organization (WHO) Questionnaire about Knowledge, Attitude and Practices (KAP) Towards Zika Virus Among Pilgrims (2017-Season)
<strong>Background: </strong>ZIKA virus is a known public health emergency of international concern. The mass gathering places like Hajj are the most viable environment for transmission of such virus. <strong>Aim of the...
Fixed Zirconia Partial Denture
<strong>Background: </strong>Ceramics have anextended history in fixed prosthodontics of attaining optimal esthetics. Yttrium tetragonal zirconia polycrystal (Y-TZP)-based systems are a recent addition to the high-streng...
Assessment of Knowledge, Attitude and Practice of Hand Hygiene among Health Care Workers in Arar City, Saudi Arabia
<strong>Background: </strong>Hand hygiene before and after each contact with any patient, is simple, easily implemented and an effective practice to prevent hospital acquired infection.This study<strong> aimed </strong>t...
Awareness of Tuberculosis Among General Populations in Riyadh Region and Its Surroundings
Background: In the past, and until the end of the twentieth century, TB was one of the major causes of death. Nowadays, the world is still challenging with TB control, even though the percentage of TB has been decreased....
Imaging View of Arterial Tortuosity Syndrome - Case Report
<strong>ABSTRACT</strong><br /> <strong>Background: </strong>Arterial tortuosity syndrome is one of the autosomal recessive diseases and caused by alterations (mutations) in the <em>SLC2A10 </em>gene. It is a rare disord...