Spectrophotometric method development and validation for the estimation of ticagrelor in bulk and its dosage forms
Journal Title: International Journal of Allied Medical Sciences and Clinical Research - Year 2019, Vol 7, Issue 1
Abstract
Simple, sensitive, accurate, precise, stability indicating UV spectrophotometric method have been developed for quantitative determination of ticagrelor in bulk and its dosage form. The UV spectrum was scanned between 200-400 nm and 254 nm was selected as maximum wavelength for absorption. Beer’s law was obeyed in the concentration range of 2-10µg/ml were found the method was successfully applied to the pharmaceutical dosage forms containing the above mentioned drug without any interference by excipients. Results of the analysis were validated as per ICH guidelines. This method can be used for the routine and quality control analysis of ticagrelor in raw material and pharmaceutical formulations.
Authors and Affiliations
Sireesha P
A review on therapeutic uses of pedalium murex
Pedalium murex is the most useful traditional medicinal plants in India.It is a small herb distributed in India, useful in development in new formulation and activities of some of this compound isolated, pharmacological...
Utilization of dates extract to suppress stomach and duodenal signal on magnetic resonance cholangiopancreatopgrapy (MRCP)
The result of the image of the biliary system on MRCP examination is often disturbed by artifacts due to signal from the stomach and duodenum. To eliminate the gastric and duodenal signal artifacts is required an intra o...
A comparative radiographic evaluation of condylar position in wax check bite record; gothic arch tracing and post insertion of complete denture
Aim To determine the position of condyle radiographically in the wax check bite stage, the Gothic arch tracing and post insertion of denture to decide the clinically comfortable position of condyle at the dentulous and e...
Pulmonary function test in petrol pump workers and garage workers: A long drawn peril
A cross-sectional study on occupational exposure to petrol vapours, diesel and automobile exhaust on pulmonary function tests was conducted. Parameters like FEV1, FVC and FEF25-75% of petrol pump workers and garage worke...
To compare immediate effect of static and dynamic stretching on sprint and jump performance in healthy school children
The aims of this study were to compare the immediate effects of stretching static and dynamic stretching on sprinting and vertical jump performance of healthy school children. Ninety healthy school children (mean age = 1...