SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF RABEPRAZOLE SODIUM IN TABLETS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2013, Vol 4, Issue 3
Abstract
A simple, rapid, accurate, economical and reproducible spectrophotometric method for estimation of rabeprazole sodium (RAB) has been developed. The method employs estimation by straight line equation obtained from calibration curve of rabeprazole sodium. Analysis was performed at 284.0nm which is absorbance maximum of the said drug in 20% v/v aqueous methanol as solvent. The method obeys Beer’s law between 4.08 – 24.5 µg/. Results of analysis were validated statistically by ICH guidelines 1996.
Authors and Affiliations
Gulshan Pandey, Koushlesh Mishra
Keywords
Related Articles
- EP ID EP135746
- DOI 10.7897/2230-8407.04341
- Views 68
- Downloads 0
IN VITRO ANTIINFLAMMATORY ACTIVITY OF FICUS BENGHALENSIS BARK
To evaluate the anti-inflammatory property of the different extract of bark of Ficus benghalensis, family Moraceae is a very large, fast growing, evergreen tree up to 30 meters, with spreading branches and many aerial ro...
FORMULATION AND EVALUATION OF FLOATING MATRIX TABLETS OF FAMOTIDINE USING NATURAL POLYMERS
In the present investigation effervescent floating matrix tablets of famotidine are formulated to achieve gastric retention for a period of 8 to 10 hrs. Famotidine is H2 receptor antagonist widely prescribed in gastric u...
A CASE REPORT OF HEMATOHIDROSIS: VERY RARE CLINICAL ENTITY
Hematohidrosis is a very rare clinical condition of blood sweating. A 10 yr female child was presented in paediatrics department with history of spontaneous bleeding from skin since five months only on mornings around 6:...
FORMULATION AND IN-VITRO EVALUATION OF NOVEL BUCCAL MUCOADHESIVE TABLETS OF FELODIPINE
The objective of this work was formulation and in-vitro evaluation of novel buccal mucoadhesive tablets of felodipine as core in cup to release and permeate the drug unidirectionally towards the buccal mucosa and to ente...