Spectrophotometric Oxidation Method for the Determination of Teneligliptin by Using Bromate - Bromide Mixture
Journal Title: International Journal of Trend in Scientific Research and Development - Year 2018, Vol 2, Issue 5
Abstract
A sensitive, precise, accurate, simple and rapid spectrophotometric method has been developed for the estimation of Teneligliptin in pharmaceutical formulations and in the drug dosage form. During the course of study, it is observed that acidic solution of the drug formed the oxidation product with Bromate "“ Bromide mixture. This property of the drug is exploited for the development of spectrophotometric method for the determination and analysis of the drug. The oxidation product showed ?max at 250 nm. The linearity range for Teneligliptin is found to be 10 µgml to 250 µgml. Recovery studies gave satisfactory results indicating that none of common additives and excipients interfere the assay method. The molar absorptivity and the sandell sensitivity of the method are evaluated and the values are found to be to be 1.1645×104 lit molecm and 0.0366 µg mlcm2 respectively. I. Lakshmi Prasanna | G. T. Naidu | G. Abdul Huq"Spectrophotometric Oxidation Method for the Determination of Teneligliptin by Using Bromate "“ Bromide Mixture" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-5 , August 2018, URL: http://www.ijtsrd.com/papers/ijtsrd18253.pdf http://www.ijtsrd.com/physics/other/18253/spectrophotometric-oxidation-method-for-the-determination-of-teneligliptin-by-using-bromate---bromide-mixture/i-lakshmi-prasanna
Authors and Affiliations
Keywords
Related Articles
- EP ID EP390011
- DOI -
- Views 72
- Downloads 0
A Study on State Bank of India’s Doorstep Banking Service
The government has imposed strict movement regulations amid the COVID 19 lockdown in the country. All bank account holders fail to withdraw their money and meet the banks directly. It has become tough to lead their life...
Why are Humans so Afraid of Insects
Fear of wild animals have been considered as an evolutionary adaptation for long period, because most of them are potential predators to humans. But less known is whether insects elicit similar fear in humans. In this pa...
Analysis of Characteristics Behaviour use of Locally Materials in Highway Subgrade
Concrete is strong in compression but weak in tension and brittle also. Cracks also start forming as soon as the concrete is placed. These above said drawbacks don't permit the use of normal concrete in pavements as they...
A Review on Rain Fade and Signal Attenuation by Rain in Ku and Ka Band Satellite Communication at MGC Campus Punjab India
Rain attenuation is a major challenge to microwave satellite communication especially at frequencies above 10 GHz, causing unavailability of signals most of the time. Rain attenuation predictions have become one of the v...
A Comparative Study on Consumer'S Behaviour towards Organized and Unorganized Retailing in Central Chennai
Retailing consists of all activities involved in selling goods and services to consumers for their personal, family, or household use. It covers sales of goods ranging from automobiles to apparel and food products, and s...