Spectrum of Acute Kidney Injury and its Clinical Profile and Outcome in Children Admitted to PICU
Journal Title: Pediatric Education and Research - Year 2018, Vol 6, Issue 2
Abstract
Objective: To determine incidence, risk factors, and outcome of acute kidney injury (AKI) in Pediatric Intensive Care Unit (PICU). Materials and Methods: This prospective observational study was conducted over period of 1½ years. All patients within the age group of 1 month to 18 years admitted in the PICU (Pediatric Intensive Care Unit) at Basaveshwar teaching and general hospital and Sangameshwar hospital attached to Mahadevappa Rampure Medical College during a period from December 2015 to August 2017. Results: Out of 1007 patient screened 7 patient were excluded, out of which 2 where congenital dysplastic kidney, 2 were known case of nephrotic syndrome, 3 where known case of chronic kidney disease. Out of 1000 patients 69 children had AKI, giving incidence of 6.9%. The median age of boys and girls were 4.56±3.84 and 4.49±4.01 respectively. 58% of the patients were boys. The median admission serum creatinine value in AKI patients was 2.91±2.48 mg/dL. In the present study, pre-renal causes accounted for (54) 78.3% of AKI. AKI Stage 1, 2, 3 was diagnosed in 11 (15.9%), 14 (20.3%) and 44 (63.8%) respectively. Conclusions: AKI continues to be associated with adverse outcomes, including high mortality , morbidity and prolonged hospital stay. Mechanical ventilation & Hypovolemia were independent risk factors. Higher the stage of AKI mortality increases. Early diagnosis of AKI using new defined criteria (AKIN, RIFLE, pRIFLE) [4,5,6] along with early and appropriate management of risk factors will prevent the progression of AKI and decrease the mortality and morbidity of AKI patients.
Authors and Affiliations
Basavaraj Patil
Keywords
Related Articles
- EP ID EP582828
- DOI 10.21088/per.2321.1644.6218.8
- Views 81
- Downloads 0
Packed Red Blood Cell Transfusion Practice in Pediatric Intensive Care Unit
Background: Transfusion of packed red blood cells is an important aspect of care in the critically ill children. The decision to administer PRC should be taken only after weighing the benefits and the risks of PRC transf...
The Endocrine Dysfunction in Multitransfused Thalassemic Patients
Background: Every year 10,000 children with thalassemia major are born in India, which constitutes 10% of the total numbers in the world. The current management of thalassemia major (TM) includes regular transfusion pro...
Clinical Profile of Patients with Febrile Convulsion: A Retrospective Study in a Tertiary Care Pediatric Hospital
Introduction: Febrile seizures (FS) occur in 2-5% of children aged 6 months to 5 years. Several studies have confirmed that between 2 to 7% of children with FS, develop epilepsy later in life. This study was performed to...
Clinical Correlates of Working Memory Deficits in School Going Children with and Without ADHD in Ahemdnagar
Both working memory and attention-deficit/hyperactivity disorder (ADHD) have been associated with educational deficits. Since working memory deficits are prevalent in children with ADHD, the main aim of the present study...
Clinical Predictors of Metabolic Acidosis in Hospitalized Children of 6-60 Months with Severe Acute Malnutrition
Context: Malnourished children are at increased risk of many common infections and their complications. In those hospitalized with Severe Acute Malnutrition (SAM), concomitant infections and diarrhoea are frequent compli...