Spectrum of Antimicrobial Sensitivity of Escherichia Coli in Sputum in a Tertiary Medical Centre in Kolkata, West Bengal, 7 Years’ Experience
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 10
Abstract
Introduction: E coli though is a normal inhabitant of human gastrointestinal tract but in case of immunocompromized patients it is responsible for producing different type of diseases involving different systems of the body. Due to irrational use of antibiotics this organism demonstrated progressively increasing resistance to different commonly used as well as highly selective antibiotics. Present study tried to demonstrate the spectrum of sensitivity to different antibiotics for E coli from the sputum of the patients. Material and methods: In this retrospective study sputum was isolated from the 1078 patients suffering from chest infections of K P C Medical College and Hospital, Jadavpur, and Kolkata and was sent to Microbiology department for culture and sensitivity. Results: Total number of E coli was 48 (4.46%). This organism was highly sensitive to carbapenem group of drugs (72.91%—85.41%), tigicycline (70.83%), polymixin B (68.75%) and colistin (64.58%) and chloramphenicol and amikacin (62.5%), netilmicin (60.41%). Amoxicillin (2.08%), oxacillin (0%), third and fourth generation cephalosporins (0% -- 27.08%), azithromycin (0%), erythromycin (2.08%) demonstrated highest resistance and aminoglycosides except amikacin and netilmicin showed moderate resistance to E coli. Conclusion: Due to injudicial use of broad spectrum antibiotics there is evidence of increasing resistance of these bacteria to very commonly used as well as highly selective antibiotics. One should do proper investigation prior to start the antibiotics. So it may be a resolution that only after getting proper sensitivity report we can use proper antibiotics. Periodic antimicrobial surveillance in case of hospital acquired infections is needed to update the guidelines on proper choice of organism specific as well as empiric antibiotics and only this can prevent the creeping of resistance to antibiotics to organism
Authors and Affiliations
Ashis Kumar Saha, Payodhi Dhar
Keywords
Related Articles
- EP ID EP424278
- DOI -
- Views 99
- Downloads 0
Evaluation of Efficacy of Ceftriaxone and Traditional Therapy of Ampicillin and Chloramphenicol in Treating Paediatric Patients with Bacterial Meningitis: A Comparative Study
Introduction: One of the medical emergencies in paediatric patients which manifests as meningeal inflammation in response to bacterial infections is bacterial meningitis. Among paediatric patients, a lot of variation exi...
Clinical Study and Management of Gastric Perforation
Introduction: Gastric perforation is one of the most serious and most overwhelming catastrophy. Perforations of peptic ulcer are third in frequencies, acute appendicitis and acute intestinal obstruction being more common...
Assessment of Correlation of Smoking and Drinking Habits with Depression Symptoms among Head and Neck Squamous Cell Carcinoma patients
Introduction: Head and Neck Squamous Cell Carcinoma are one of the most common oral malignancies affecting individuals worldwide. Smoking and drinking are autonomously and synergistically connected with an expanded dange...
Assessment of Risk Factors for development of Polycystic Ovarian Syndrome
Introduction: Polycystic ovary syndrome (PCOS) is a common endocrine disorder mostly due to hormonal imbalances. There could be more than one predisposing factors that can contribute for development of PCOS. However ther...
Assessment of Efficacy of Amlodipine with Cilnidipine in Hypertensive Patients: A Comparative Study
Introduction: The major problem encountered in treatment patients of hypertension and diabtetic patients with hypertension is controlling their Systolic blood pressure (SBP) and Diastolic blood pressure (DBP). One of the...