Spectrum of Cirrhosis of Liver in Eastern Madhya Pradesh, India
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 2
Abstract
Background: - In India, etiology of cirrhosis varies with geographical areas. Aim: - To evaluate etiological and clinical spectrum of cirrhosis in eastern Madhya Pradesh state of India. Methods: - The study includes 125 cirrhotic patients (aged >14yrs) diagnosed by clinical, biochemical and radiological parameters admitted in NSCB medical college, Jabalpur between 2009 and 2011. All patients underwent routine lab investigations, and tests for hepatitis B and hepatitis C virus. Tests for Autoimmune, Wilson’s disease and Haemochromatosis were also done. Patients were treated and outcome was noted. Results: - Mean age was 52 ± 10 Years, male constituted 71.2% cases. Alcoholism was seen in 36.8%, HBV in 36.8% and HCV in 3.2% cases. Wilson’s disease, cardiac cirrhosis was seen in 1(0.8%) patient each. No etiology could be found in 20.8% patients. Commonest presentation was ascites in (84.8%), followed by jaundice (60%), gastro-intestinal bleed (38.4%), Hepatic encephalopathy (18.4%), Hepatorenal syndrome (12%) and Spontaneous Bacterial peritonitis (4.0%). Maximum patients were in Child’s Pugh B class (49%). Main cause of mortality was HE and HRS; maximum deaths occurred in Child’s C. Conclusion: - Alcohol and HBV were major etiologies. Most common presentation was ascites and jaundice and maximum mortality was seen in Child’s C.
Authors and Affiliations
Rahul Trimukhe
Keywords
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- EP ID EP591698
- DOI 10.9790/0853-1602030608.
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