Spectrum of CT findings in gall bladder carcinoma patients in north Indian population
Journal Title: International Journal of Medical Research and Review - Year 2017, Vol 5, Issue 5
Abstract
Gallbladder cancer is the most common malignancy of the biliary tract, representing 80% - 95% of biliary tract cancers worldwide [1]. It ranks fifth among gastrointestinal cancers [2]. In India, gall bladder cancer is more prevalent in north and north-eastern regions of the country while Southern India has low incidence rate in both the sexes [3,4,5]. Gall bladder cancer is more frequent in elderly people with female preponderance [5]. This cancer develops rapidly and silently with early diagnosis of gallbladder carcinoma difficult because most patients present with nonspecific findings of right upper quadrant pain, malaise, weight loss, jaundice, anorexia, and vomiting. This presentation is often confused with symptomatic cholelithiasis or chronic cholecystitis. Gallbladder carcinoma may present as mass completely occupying or replacing the gallbladder lumen( in 40–65% of cases), focal or diffuse asymmetric gallbladder wall thickening( in 20–30% of cases)or an intraluminal polypoid lesion( in 15–25% of cases[6,7,8,9]. Associated findings may be cholelithiasis, bile duct dilatation, invasion of the adjacent structures, distant metastasis other than those in the liver and porcelain gallbladder. Ultrasound is often the initial and most commonly used imaging modality for suspected gallbladder pathology because of its low cost and widespread availability. Accurate diagnosis may be difficult using sonography because thickening of the gallbladder wall is nonspecific finding. However, CT has become popular for evaluating the acute abdomen and often has been found as first modality to detect and characterize gallbladder wall thickening and other pathologies [10]. It may be used as an adjunct to an inconclusive sonography or for staging of disease.
Authors and Affiliations
Pushpinder Singh, Navkiran Kaur, Mandeep Kaur
Keywords
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- EP ID EP272835
- DOI 10.17511/ijmrr. 2017.i05.11
- Views 81
- Downloads 0
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