Spectrum of Endometrial Pathology in Abnormal Uterine Bleeding
Journal Title: International Journal of Health Sciences and Research - Year 2017, Vol 7, Issue 9
Abstract
Background: Abnormal uterine bleeding (AUB) is defined as any alteration in the pattern or volume of menstrual blood flow. It is a very common gynecological condition and has a major impact on quality of life. In many instances it is related to the endometrial pathology. The study was done to evaluate the histopathology of endometrium for identifying endometrial causes of AUB and their incidence in different age groups. Materials and methods: The study was done at a tertiary care institute over a period of one year from 1st January 2016 to 31th December 2016. Endometrial samples and hysterectomy specimen of patients with AUB, in whom non-endometrial pathology had been ruled out, were included in the study. The specimens were routinely processed and H&E stained slides were studied for endometrial pattern. Results: Total of 248 cases were received, 150 endometrial tissue samples and 98 hysterectomy specimens. There were 49.2% women in perimenopausal (40-49 years), 26.2% in reproductive (<40 years) and 24.6% in post menopausal age group (>49 years). Well defined organic abnormality was present in 33.9%. Endometrial patterns included cyclic (36.7%), disordered proliferative (16.1%), atrophic (13.3%), chronic endometritis (2.4%), endometrial polyp (8.1%), endometrial hyperplasia (21%) and endometrial carcinoma (2.4%). Conclusions: Patients with AUB show a varying spectrum of endometrial pattern, ranging from cyclic endometrium to carcinomas. It is therefore important to evaluate for endometrial pathology in all women presenting with AUB without a known cause.
Authors and Affiliations
Dr. Nivedita Singh
Keywords
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