Spectrum of Findings on HRCT in Evaluation of Interstitial Lung Diseases: A Single Centre Prospective Observational Study

Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11

Abstract

Background: Evaluation of the involvement pattern of pulmonary interstitium in suspected cases of Interstitial lung diseases with the help of HRCT and chest radiographic findings and then to arrive at a conclusive diagnosis,comparing accuracies of both modalities. Objectives: To compare the accuracies of chest radiography and HRCT in the prediction of specific diagnosis of interstitial lung diseases as well as to study the demographic profiles of cases of ILD presenting to a tertiarycare hospital Method : We investigated 40 patients having symptoms related to suspected Interstitial lung disease with laboratory investigations & imaging modalities like Chest X-ray&HRCT Thorax in our institution, Medical College, Kolkata, (a tertiary care hospital) for a period of 1 year from January, 2017 to December, 2017. We compared the clinical characteristics of patients with HRCT findings of ILD and classified the types of ILD according to the pattern of pulmonaryinterstitial involvement, the incidence of disease in males & females, age of incidence etc. Results:24 of the cases were females constituting 60% of the cases,and 16 were males constituting 40%.Rheumatoid arthritis,progressive systemic sclerosis and systemic lupus erythematosus were more in females. Idiopathic pulmonary fibrosis and pulmonary Koch’s infections were common in males.Cases with pulmonary Koch’s were the largest group in our study, constituting 27.5% of total number of cases,followed by progressive systemic sclerosis and rheumatoid arthritis(17.5%) each.The most number of cases of Pulmonary Koch’s infection were noted in 3rd and 4th decade of life. The most number of cases with rheumatoid arthritis and progressive systemic sclerosis were in 5th and 6th decades. The positive predictive value of HRCT for ILDs was 97.22% which was foundto be superior to that of chest Xrays(93.93%) Conclusions: Most detailed and precise diagnostic conclusion can be made only with HRCT scans,because HRCT scans can reveal up to the level of secondary pulmonary lobule,thereby closely correlating with histopathology. HRCT is more sensitive and specific in diagnosing most of the ILDs. Moreover, it helps us in describing disease extent and prognosis.Therefore we conclude that HRCT scan in the best non-invasive diagnostic modality in the evaluation of interstitial lung disease.

Authors and Affiliations

Dr. Nupur Basu, Dr Averee Gangopadhayay

Keywords

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  • EP ID EP416327
  • DOI 10.9790/0853-1711075363.
  • Views 66
  • Downloads 0

How To Cite

Dr. Nupur Basu, Dr Averee Gangopadhayay (2018). Spectrum of Findings on HRCT in Evaluation of Interstitial Lung Diseases: A Single Centre Prospective Observational Study. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), 17(11), 53-63. https://europub.co.uk/articles/-A-416327