Spectrum of infection in children with steroid responsive nephrotic syndrome
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 5
Abstract
Abstract: Infection in patients with nephrotic syndrome has been described as hallmark of idiopathic nephrotic syndrome. The aim of present article is to study the clinical profile of infections in children with steroid responsive nephrotic syndrome and correlation of serum albumin and serum cholesterol level with episodes of infection in children with steroid responsive nephrotic syndrome. The predictive value of C-reactive protein in cases of suspected infection in children with nephrotic syndrome was also taken into consideration. This cohort study comprised of minimum of 62 children from November 2008 to October 2010 with steroid responsive Nephrotic syndrome presenting with symptoms of infections to Hindu Rao Hospital Emergency/ward/Nephrology clinic and follow up of children attending the nephrology clinic at monthly interval. Among steroid responsive nephrotic syndrome children we found most common infection was upper respiratory tract infection (65.1%) followed by acute diarrhoea 23.15%, Urinary tract infection 2.34%, pneumonia 1.67%, tuberculosis 1.34%, septicaemia + peritonitis1.34% , chronic suppurative otitis media 1%, miscellaneous 4.36 %. On evaluation of biochemical parameter of nephrotic syndrome our study revealed total protein, albumin were significantly (p<0.05) lower and cholesterol was significantly higher on comparing infection with no infection during relapse. CRP was positive during pneumonia, septicaemia, peritonitis. Infections are more common in frequent relapse and steroid dependent nephrotic syndrome children. CRP is useful as a marker during invasive bacterial infection. Keywords:Albumin,Infections,Nephrotic syndrome,Steroids
Authors and Affiliations
Payal Mittal, D. K. Bhagwani, Pranav Gupta, Abhishek Singh
Keywords
Related Articles
- EP ID EP372668
- DOI -
- Views 60
- Downloads 0
A case report of erosive lichen planus of the oral mucosa
Oral lichen planus mostly affects middle-aged females. It is a chronic muco-cutaneous autoimmune disease and factors like psychological stress, systemic conditions or drugs are the possible etiological conditions. Varian...
Unilateral myelinated retinal nerve fibers associated with ipsilateral myopia and amblyopia
Abstract: The objective is to evaluate the clinical features of unilateral myelinated retinal nerve fibers (MRNF) associated with ipsilateral myopia and amblyopia.We retrospectively analyzed three patients with unilatera...
Benign Eyelids, Conjunctival, Intraocular and Orbital Tumors in Children: Epidemiology and Review of Literature
Benign eyelid, conjunctival, intraocular and orbital tumors are the most common neoplasm in daily ophthalmology practice. Benign tumors largely predominated over malignant ones, representing about 84% of cases in many s...
Evaluation of Effect of Different Enamel Surface Preparation Methods on Shear Bond Strength and Enamel Surface Texture
In an attempt to minimize bond failures, orthodontists have sought out ways to ensure adequate bond strengths while still maintaining an efficient procedure with the least invasive method of bonding. Enamel loss with aci...
NSAID Induced Gastritis and its Prevention through Education
Abstract:Aim of this study is to study the prevalence of drug induced gastritis in general population and to take measures to prevent NSAID induced Gastritis through proper counseling and education. More than 15000 rural...