Spectrum of Magnetic Resonance Imaging Findings in Fungal Infections of Brain
Journal Title: International Journal of Contemporary Medicine surgery and Radiology - Year 2018, Vol 3, Issue 2
Abstract
Introduction: Fungal infections of the brain are common and fatal if not diagnosed and treated timely. Despite the general lack of diagnostic specificity, certain findings are more commonly associated with particular fungal pathogens. We, in the present series, evaluate the magnetic resonance imaging (MRI) features and correlate the neuroradiological diagnosis with the nature of fungal pathogens. Study aimed to analyze MRI features in fungal infections of brain and correlate radiological diagnosis with clinical and histopathological diagnosis. Materials and Methods: This study was conducted on patients with suspected / previously diagnosed cases of CNS infections referred to the department of Radiodiagnosis at Dayanand Medical College, Ludhiana over one year. MRI was performed on MAGNETOM Avanto 18 Channel 1.5 Tesla TM MR Machine by Siemens India Ltd.MRI protocol consisted of the Turbo spin echo (TSE) T2W sequence, Spin echo (SE) T1W sequence, FLAIR, GRE, DW and Post-gad T1W sequences. Results: In the present study, we found that fungal infections occur more commonly in the middle and old age group with some predisposing risk factor or with primary focus elsewhere. Fungal cerebral abscesses may have central restricted diffusion, apart from the well-recognized pattern, with restriction in the wall and intrapillary projections. Oculorhinocerebral pathology with bone destruction usually has fungal etiology. Conclusion: Cerebral infarcts in immunocompromised individuals, with or without significant meningeal enhancement, may be due to cryptococcosis. Aspergillosis may manifest as an extradural lesion mimicking a meningioma or intraaxial butterfly glioma.
Authors and Affiliations
Kamini Gupta, Avik Banerjee, Kavita Saggar
Keywords
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- EP ID EP424478
- DOI 10.21276/ijcmsr.2018.3.2.33
- Views 103
- Downloads 0
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