SPECTRUM OF PROSTATIC LESIONS IN A TERTIARY CARE HOSPITAL- A 5½-YEAR RETROSPECTIVE DESCRIPTIVE STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 36
Abstract
BACKGROUND The incidence of prostatic lesions increases with increasing age. The most important diseases of prostate are inflammatory lesions (prostatitis), nodular hyperplasia (benign prostatic hyperplasia) and carcinoma. Prostatic carcinoma is the second most common cancer in males. Prostatic cancer is usually diagnosed histopathologically based on morphological features like growth pattern, nuclear atypia and absence of basal cells. Establishing or ruling out the diagnosis of carcinoma of prostate has been a challenging task for pathologists for many years. MATERIALS AND METHODS The present study was a retrospective descriptive study for all the prostatic specimens received between January 2013 and June 2018. The haematoxylin and eosin stained slides were retrieved and reviewed. RESULTS The present study constituted a total of 321 cases with age ranging from 30 years - 85 years. All prostatic specimens were broadly classified into non-neoplastic and neoplastic lesions. The present study included 321 prostatic specimens which comprised of 02 prostatic biopsies, 318 Transurethral Resection of Prostate (TURP) chips and 01 prostatectomy specimens. Out of total 321 cases, non-neoplastic were 279 cases (86.91%) and neoplastic were 42 (13.09%) cases. Most common non-neoplastic lesion was nodular hyperplasia 278 cases, of which 117 cases were affected by prostatitis. Out of total nodular hyperplasia with prostatitis, 05 cases were showing granulomas and 112 cases were showing prostatitis (non-granulomatous). In the present study, neoplastic lesions were 42 cases, out of which low-grade Prostatic Intraepithelial Neoplasia (PIN) were 15 cases (37.7%), adenocarcinoma 25 cases (59.5%) and other neoplasms 02 cases (4.7%). CONCLUSION Our study concluded that Benign Prostatic Hyperplasia (BPH) is the commonest lesion among males with features of prostatism and most common type of inflammation associated with BPH is chronic inflammation. The commonest age group affected by both carcinoma and BPH is the seventh decade.
Authors and Affiliations
Satyasri K, Sweta Sinha, Kartheek B. V. S
Keywords
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- EP ID EP545007
- DOI 10.14260/jemds/2018/891
- Views 80
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