Spontaneous splenic rupture in a teenager as first manifestation of acute myeloid leukemia: Case report and literature review
Journal Title: Journal of Health and Social Sciences - Year 2018, Vol 3, Issue 3
Abstract
Spontaneous splenic rupture is a well-known, but rare life-threatening complication of hematological malignancies. We describe the case of a 12-year-old boy with a 5-day history of fever and successively left upper quadrant abdominal pain and sudden clinical deterioration necessitating emergency splenectomy. On arrival, a blood dyscrasia was postoperatively confirmed as acute myeloid leukemia. Cases of atraumatic rupture in diseased spleens are widely reported and pathological rupture of the spleen is a rare, but well recognized complication in hematological malignancies. This case report represents a rare and fatal initial presentation of acute myeloid leukemia in an adolescent. Because of the rarity of atraumatic splenic rupture, a high index of clinical suspicion must be maintained in patients with left upper quadrant pain and abnormal differential count on peripheral blood smear.
Authors and Affiliations
Antonio Villa, Simona Rossi, Isabella Riva, Cecilia Tedesco, Francesca Maria Zanchettin, Rinaldo Chiumento
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