Staphylococcus lugdunensis Endocarditis in A Patient Being Treated for Pyelonephritis

Journal Title: Journal of Microbiology and Infectious Diseases - Year 2018, Vol 8, Issue 1

Abstract

A 35 years old female with known chronic left pelvo-ureteric junction (PUJ) obstruction presented with recurrent pyrexia and left loin pain and was treated for pyelonephritis. She had a history of severe aortic valve (AV) regurgitation. After five days of broad spectrum antibiotics and a percutaneous nephrostomy, her fevers persisted. Staphylococcus lugdunensis was isolated from her blood culture and she was diagnosed with mitral valve endocarditis following an echocardiogram. She was transferred to a tertiary cardiothoracic unit where she underwent a mitral and aortic mechanical valve repair. After 6 weeks of intravenous antibiotic treatment she was discharged without signs of infection but with poor cardiac function. S. lugdunensis is a virulent organism which is thought to be underdiagnosed and is associated with aggressive and destructive endocarditis. An awareness of the organism as well as prompt diagnosis and treatment with effective multi-disciplinary management is needed to avoid substantial morbidity in these patients. Whilst S. lugdunensis is known to cause invasive endocarditis, it has never been reported following pyelonephritis. The significance of this case is that despite receiving appropriate and timely treatment the patient was left with deteriorating cardiac function. This is an important reminder that this organism must be taken seriously when isolated in the context of infection. J Microbiol Infect Dis 2018; 8(1):37-40 Keywords:

Authors and Affiliations

Christopher M Peake, Nicholas Faure-Walker, Elli DeMertzi

Keywords

Related Articles

Serum interleukin-6, interleukin -10, tumor necrosis factor -alpha, neopterin and plasma soluble urokinase plasminogen activator receptor levels in the patients with pandemic H1N1 influenza infection 

Objective: This study aims to investigate the clinical importance of serum interleukin (IL) 6, IL-10, tumor necrosis factor alpha (TNF-alpha), neopterin, and plasma soluble urokinase plasminogen activator receptor (...

Middle East Respiratory Syndrome: MERS

Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly emerging respiratory virus. It was first identified in Saudi Arabia in 2012. MERS-CoV infection is characterized by a spectrum of illness ranging from mi...

Use of hematological parameters in evaluation of treatment efficacy in cutaneous leishmaniasis

Objective: In the present study we investigated the role of hematological parameters, including neutrophil/lymphocyte ratio and platelet/lymphocyte ratio, mean platelet volume and platelet distribution width in the evalu...

Severe Respiratory Tract Infections with Human Bocavirus in Children

Acute respiratory tract infection remains a major cause of childhood hospitalization and mortality in young children. Human bocavirus (HBoV) is a virus belonging to the Parvoviridae family, which has been newly discovere...

Abiotrophia defectiva: A Rare Gut Pathogen Resulting Endocarditis in Inflammatory Bowel Disease

Abiotrophia defectiva (formerly referred to as nutritionally variant Streptococcus) is a normal flora of the human gastrointestinal tract. Abiotrophia defectiva is associated with high morbidity and mortality, yet timely...

Download PDF file
  • EP ID EP422954
  • DOI 10.5799/jmid.404245
  • Views 131
  • Downloads 0

How To Cite

Christopher M Peake, Nicholas Faure-Walker, Elli DeMertzi (2018). Staphylococcus lugdunensis Endocarditis in A Patient Being Treated for Pyelonephritis. Journal of Microbiology and Infectious Diseases, 8(1), 37-40. https://europub.co.uk/articles/-A-422954