Status of high sensitive C- reactive protein (hs-CRP) in NAFLD obese type-2 diabetic subjects
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 3
Abstract
Introduction Non alcoholic fatty liver disease NAFLD is a disease occurring in patients without any significant alcohol consumption It includes a broad spectrum and advanced forms of liver diseases from simple steatosis to nonalcoholic steatohepatitis fibrosis and cirrhosis and is associated with diabetes mellitus insulin resistance obesity dyslipidemia and metabolic syndrome The aim of this study is to evaluate the metabolic significance of NAFLD in obese and type2 diabetic subjects compare to healthy group of individuals and those independent factors associated with NAFLDMaterials and Methods Our study was conducted in Govt Medial College Banda UP as well as G R Medical College Gwalior MP A total of 200 subjects were involved in our study diagnosis being based on ultrasonography Out of these 100 were obese with type2 diabetic patients and 100 were healthy subjects They were evaluated by measurement of BMI and several biochemical blood parameters such as fasting blood glucose lipid profile liver function tests ALT ALP and GGT and hsCRP levelResults An increase in the BMI and levels of FBS total cholesterol triglycerides LDL VLDL GGT ALT ALP and hsCRP level and a decrease in HDL was observed in NAFLD group of individuals The values of these biochemical markers were found higher in NAFLD patients and the variations were found to be statically significant BMI and triglycerides were positively correlated with fatty liverConclusion Obesity hyperglycemia dyslipidemia and increased liver enzymes and hsCRP level are seen more commonly in non alcoholic fatty liver in type2 diabetic obese patientsKeywords NAFLD BMI High sensitive Creactive protein
Authors and Affiliations
Sanjeev Kumar Singh, Dharmveer Sharma, Nivedita Singh, Raj Kumar, Pavan Gautam5
Keywords
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- EP ID EP475178
- DOI 10.18231/2394-6377.2018.0075
- Views 77
- Downloads 0
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