Stem cells and skin regeneration.
Journal Title: Folia Histochemica et Cytobiologica - Year 2011, Vol 49, Issue 3
Abstract
Stem cells represent a great hope for regenerative medicine. In adult life, stem cell deposits are kept in organ niches; the need for tissue or organ regeneration mobilizes stem cells via the SDF-1-CXCR4 regulation axis. Constant regeneration of the skin is achieved due to stem cell differentiation within the epidermis and the hair follicle; thus, skin may serve as an excellent source of stem cells. This is of paramount importance in the treatment of chronic skin wounds and burns. (Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 3, pp. 375-380).
Authors and Affiliations
Marzena Staniszewska, Sylwia Słuczanowska-Głąbowska, Justyna Drukała
Keywords
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Stem cells represent a great hope for regenerative medicine. In adult life, stem cell deposits are kept in organ niches; the need for tissue or organ regeneration mobilizes stem cells via the SDF-1-CXCR4 regulation axis...