Stepping on diagnosis with step sections- An institutional experience
Journal Title: IP Archives of Cytology and Histopathology Research - Year 2018, Vol 3, Issue 1
Abstract
Introduction A thorough morphological assessment plays a central role in evaluation of skin biopsies Overlapping microscopic features pose additional diagnostic challenges in dermatopathological practice More over skin biopsies are of small size and diagnostic findings may not be present in the initial section Hence step sectioning may have added value as in adjunct in contemplating the final diagnosisObjective The study was aimed to evaluate the diagnostic utility of step sectioning in dermatopathologyMaterials and Methods A total of 478 skin biopsies were received over a period of 2 years from January 2015 to December 2016 at the Department of Pathology JJMMC Two prospective step sections A2 A3 were cut at an interval of 50microm from the original section A1 The findings were evaluated by two pathologists independently The results were analysed and evaluated statisticallyResults Majority of cases n 453 947 were diagnostic Out of these many cases n 400 836 showed no additional findings on step sections In a few cases n 32 67 step section provided additional findings which contributed to the diagnosis There were some cases n 14 3 in which findings were noted only on step section leading to the diagnosis Some cases n7 146 were such that the step sections changed the diagnosis made on original sectionConclusion Step sectioning enhances the diagnostic accuracy of morphological assessment in ermatopathology practiceKeywords Prospective Step sections Skin biopsy Lichen planus
Authors and Affiliations
Vardendra Kulkarni, Sushmita. H, Seema Bijjaragi, Prakash Kumar
Keywords
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- EP ID EP490536
- DOI 10.18231/2456-9267.2018.0006
- Views 109
- Downloads 0
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