STEREOTACTIC BODY RADIOTHERAPY (SBRT) AND OLIGOMETASTATIC BLADDER CANCER: ABOUT A CASE AND REVIEW OF THE LITERATURE
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 1
Abstract
Purpose: The term “oligo-metastasis” could be defined as a transition state between localized and widespread systemic cancer. In the uro-oncology field, very few cases of oligo-metastases of bladder cancer have been described, probably because of the high metastatic potential of muscle invasive bladder cancer. In fact, bladder cancer remains an important cause of morbidity and mortality, the latter being predominantly related to metastasis. Herein we report a case of an oligometastatic bladder cancer treated by SBRT and we review the literature on the treatment of this disease. Methods: We describe a case of pulmonary and lymph-node metastases of a high grade bladder cancer, which relapsed after surgical resection and chemotherapy. Results: After the patient was treated with SBRT at his 3 metastatic lesions, and dispite a transient episode of grade 2 dyspnea, he was clinically in good condition without any evidence of disease on PET-CT scan after 22 months. Conclusion: SBRT is an efficient metastasis-directed treatment, and may be an alternative to chemotherapy or surgery. However, our case highlights that SBRT although easily feasible is not without any risk and should be use with caution, especially outside recognize indications and clinical trials.
Authors and Affiliations
Mane Maimouna
Keywords
Related Articles
- EP ID EP672460
- DOI -
- Views 120
- Downloads 0
TAY SACH’S DISEASE, A GENETIC MUTATION: MECHANISM OF ONSET OF DISEASE AND PHYNOTYPIC CHARACTERIZATION
Tay sach disease is a genetic disorder. It is a storage disease in which due to mutation in gene present on chromosome no 15 called HexA gene. This gene is responsible for production of hexoaminidase enzyme. This enzyme...
MOLECULAR BIOLOGICAL AND GENETIC MECHANISMS CARCINOGENESIS OF COLORECTAL CANCER (REVIEW)
Colorectal cancer (CRC) is a malignancy that begins in the colon or rectum. Colon cancer (CC) and rectal cancer (RC) are often grouped together because they have many common features. CC is one of the most common types o...
PREVALENCE OF AMELOBLASTOMA AND ITS CLINICAL AND HISTOPATHOLOGICAL FEATURES: A RETROSPECTIVE STUDY
Introduction: Prevalence of ameloblastoma has been established worldwide but collective data of ameloblastoma in Southeast Asian countries has not been well analyzed. Aim: To report prevalence and clinical features of am...
SPECTRUM OF DISEASE AND DIAGNOSTIC VALUES OF ULTRASOUND IN INMATES OF A CORRECTIONAL FACILITY IN NIGERIA
Summary: Prisons globally are associated with high medical care needs compared with the general population. In developing Countries such as Nigeria, the prisons have been in deplorable conditions including increase in di...
COMPARISON BETWEEN SUTURED AND SUTURELESS GLUE FREE CONJUNCTIVAL AUTOGRAFT IN PRIMARY PTERYGIUM
Purpose: To compare the outcome of two techniques used in the management of primary pterygium. Methods: A retrospective comparative study from medical records of patients suffering from primary pterygium treated by excis...