Steroids Effect as Adjuvant Therapy toward Length of Stay and Clinical Symptoms in Pediatric with Pneumonia
Journal Title: Indonesian Journal of Clinical Pharmacy - Year 2017, Vol 6, Issue 3
Abstract
Steroid therapy in children with pneumonia is an adjuvant therapy that has inhibitor inflammatory activity which can suppress the expression of proinflammatory cytokines and potentially prevent the inflammatory response. Some studies showed that steroids did not give beneficial effects in the treatment of patients with pneumonia, while the other studies showed that steroids can reduce the length of stay in hospital. The purpose of this study was to observe the effect of steroid on the length of stay and clinical symptoms in pediatric patients with pneumonia. This was an observational study with a prospective method in patients with pneumonia in PKU Muhammadiyah Bantul Hospital Yogyakarta from September 2015 until January 2016. A total of fifty one patients participated as subjects of this study. This study consisted of two groups, which were non‑steroid group (n=25) and steroid group (n=26). Group of non‑steroid and steroid had average value of length of stay of 5 (3–10) days and 4 (3–10) days, respectively. The duration of clinical symptoms of patients in the steroid and non‑steroid group in a row was 2 (0–6) days and 2 (0–7) days for symptoms of fever, 4 (1–10) days and 5 (2–10) days for symptoms of cough, 1 (0–5) days and 1 (0–10) days for symptoms of shortness, and 1 (0–5) days and 1 (0–9) days for symptoms of retraction. The conclusion of this study is steroid has not given significant effects on the length of stay and clinical symptoms in pediatric patients with pneumonia.
Authors and Affiliations
Sulistia Ardyati, Nurcholid U. Kurniawan, Endang Darmawan
Keywords
Related Articles
- EP ID EP370109
- DOI 10.15416/ijcp.2017.6.3.181
- Views 70
- Downloads 0
Vitamin D Receptor (VDR) and Phosphatidylinositol 3-Kinase (PI3K) Independently Affected Colorectal Adenocarcinoma Differentiation
Targeted therapy in carcinoma colorectal such as is as calcitriol and Phosphatidyl Inositol 3 Kinase (PI3K) is an alternative therapy for better treatment outcome. The aim of this study was to determine the correlation b...
Effect of Pharmacist Home Care on Adherence of Hypertensive Patients
Based on data from Basic Health Research on 2013, the prevalence of hypertension was up to 25.8%. Hypertension can be controlled by taking medication regularly and healthy lifestyle. Factor that can improve the success o...
Association between Perceived Value and Self-Medication with Antibiotics: An Observational Study Based on Health Belief Model Theory
High prevalence of self medication with antibiotics can increase the probability of irrational use of antibiotics which may lead antibiotics resistance. Thus, shifting of behavior is required to minimize the irrational u...
Impact of Self Efficacy on Innovative Behaviour Pharmacist in Hospital
Hospitals are always required in order to improve the quality of service in accordance with professional standards in accordance with their code of ethics. Therefore, health workers in hospitals, especially pharmacists,...
Formulation of the Model Fluconazole Eye Drop and Its Comparison with the Available Fluconazole Eye Drops
The aim of the study was to formulate the model formulation of fluconazole eye drop and then compare it with the available eye drops. The corneal permeation studies were conducted using freshly excised sheep cornea, moun...