Stevens - Johnson Syndrome Induced by Sorafenib for Hepatocellular Carcinoma
Journal Title: International Journal of Clinical Dermatology & Research (IJCDR) - Year 2016, Vol 4, Issue 2
Abstract
Background: Sorafenib is a new therapeutic agent being used in hepatocellular carcinoma, renal cell carcinoma and malignant melanoma. The most frequently seen cutaneous side effects due to sorafenib are erythema, exfoliative dermatitis, acne vulgaris and hand-foot skin reaction. Erythema multiforme, stevens-johnson syndrome are rare side effects of sorafenib. Observation: We present a 34-years-old woman with stevens-Johnson syndrome induced by sorafenib for hepatocellular carcinoma. Conclusion: Patients treated with sorafenib for HCC should be monitored closely with a multidisciplinary approach, and if SJS is diagnosed, these patients cannot be given sorafenib again.
Authors and Affiliations
Chakiri Radia
Unilateral Nevoid Hyperkeratosis of the Nipple and Areola Treated Successfully With Carbon Dioxide Laser
Nevoid hyperkeratosis of the nipple and areola (NHNA), is a rare benign condition characterized by papular warty excrescences on the nipple, the areola or both. We report a female patient with this rare condition appeare...
Validation of The Cardiff Acne Disability Index Questionnaire in Patients with Acne in Morocco
Background: Acne is a common distressing disease that can affect quality of life (QoL). The aim of the study was to translate and adapt the original version of the Cardiff Acne Distability Index (CADI) questionnaire from...
Subcutaneous benign Fibrous Histiocytoma of upper eyelid: A Review of the histopathological Database at a Single Faculty in Japan
A 57 year-old Japanese man presented with an asymptomatic, 7 mm subcutaneous nodule on his right upper eyelid. Findings of histopathology and immunohistochemistry led to the diagnosis of benign fibrous histiocytoma (BFH...
Paraneoplastic Dermatomyositis: About 9 Patients
Dermatomyositis, a rare inflammatory disease possibly of autoimmune origin, produces a characteristic skin rash and symmetrical proximal myopathy. Patients with Dermatomyositis have a higher incidence rate of cancer, com...
Primary Cutaneous Large B Cell Lymphoma, Leg Type: Good Evolution of A Particular Location
Primary cutaneous large B-cell lymphoma, leg type, is a rare and aggressive neoplasm as defined by the recently updated World Health Organization–European Organization for Research and Treatment of Cancer classification...