Stochastic Mathematical Models of Carcinogenesis
Journal Title: International Journal of Cancer Studies & Research (IJCR) - Year 2012, Vol 1, Issue 1
Abstract
Geneticists and molecular biologists have demonstrated that carcinogenesis is a stochastic multi-stage process with each cancer tumor being derived from a single stem cell which has sustained a finite number of genetic and/or epigenetic changes (Tan 1991, Wienberg 2007, Tan, Chen and Zhang, 2008). These genetic and/ or epigenetic changes initiate and facilitate cancer progression by driving and disturbing some relevant molecular signal pathways to promote cell proliferation and growth of cancer stem cells.
Authors and Affiliations
Wai-Yuan Tan
Keywords
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Stochastic Mathematical Models of Carcinogenesis
Geneticists and molecular biologists have demonstrated that carcinogenesis is a stochastic multi-stage process with each cancer tumor being derived from a single stem cell which has sustained a finite number of genetic a...