Structural Asymmetries of inferior Triangular Gyri, Heschl`S Gyri and Globus Pallidi in Children- A Voxel Based Morphometric Assessment of Primary and Secondary Language Areas in Children
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 11
Abstract
Background and Purpose: The objective was to assess language lateralization based on the volumetric analysis involving Inferior Triangular Gyrus (ITG),Inferior Opercular Gyrus (IOG), Superior Temporal Gyrus (STG), and secondary language areas like Heschl’s Gyrus (HG), Hippocampus , Globus Pallidi (GP), Putamen and Thalamus. Methods: Thirty six right handed children with normal brain MRI were selected for the study. Using Voxel Based Morphometry (VBM) structural volumetric differences between ITG, IOG, STG, HG, Hippocampus and thalami of right and left hemispheres were assessed by VBM, an automated technique that identifies differences in the local gray matter volume between groups using high-resolution T1-weighted MRI. Results: There was significant increase in the volume of left GP compared to the right GP (<0.001), left ITG compared to right side (p<0.03), left Heschl`s Gyrus compared to the right side (p<0.05) while the mean grey matter volume of right put a men and right IOG was larger compared to the left with a p value of 0.04 and 0.007 respectively. No significant differences in the mean grey matter volume was seen between right and left hippocampus, thalami and STG (p =0.30, 0.795 and 0.175 respectively). Conclusion: Our study highlights the importance of left ITG,HG and GP in language processing.
Authors and Affiliations
Dr Sanjeev V Thomas
Keywords
Related Articles
- EP ID EP521902
- DOI -
- Views 50
- Downloads 0
Evaluation of Outcome Determinants in Snakebite Victims in A Rural Medical College of South Bengal
Background: Snake bite is a neglected public health problem in India. Hence, identification of the clinical parameters as reliable determinants of mortality which may be used at peripheral levels of health care, is essen...
Study of Prevalence of Hemoglobinopathies by HPLC in Central Gujarat
Objectives: To evaluate Prevalence and geographical distribution of various hemoglobinopathies in central Gujarat by using HPLC. Method: Hemoglobinopathies were evaluated by prospective study on BIORAD variant of HPLC (H...
RBC is most and Lymphocyte Least Commonly Effected Hematological Cell in for Acute Aluminium Phosphide Poisoning (AALPP) Patients
Aims & Objectives: Exclude the EDTA induced storage artifacts .Identify and excludes the misinterpretation of peripheral blood smears examination. Identify the EDTA induced RBC & WBC morphological storage artifacts. Iden...
A study on the expressions of Ki-67 and Cyclin-D1 in oral pre malignant lesions
Objective: To evaluate the expressions of Ki-67 and Cyclin-D1 in oral pre malignant lesions. Methods: This was a prospective observational study. Clinical history was taken from all the cases with more stress on probable...
Variation of Prolidase Activity: A Predictor of Neuropathy due to Diabetes Mellitus?
Prolidase is a member of the matrix metalloproteinase family responsible for collagen turnover which is implicated in the pathogenesis of diabetic neuropathy (DN). 50 (F-16, M-34) subjects suffering from T2DM, 46 subject...