Structural peculiarities of m. quadriceps of femur in experimental rats in the conditions of femur deformity forming

Journal Title: Orthopaedics, Traumatology and Prosthetics - Year 2016, Vol 602, Issue 1

Abstract

Stable posttraumatic deformities of long bones lead to changes in interrelationships in damaged segments that could cause dysfunction of muscles and ligaments, joint surface integrity and range of motion in limb joints. The goal: to investigate in experiment on rats the structural peculiarities of muscles adjacent to peak of posttraumatic femur diaphysis deformity. Methods: varus deformity on the level of middle third of femur diaphysis was simulated on 15 white mature rats (age at the beginning of study — 6 moths). Preshaped K-wire (with appropriate size and angle 35°) was inserted in the intramedullary canal after transversal osteotomy to create deformity. Euthanasia was performed 1, 3 and 6 moths after operation followed by histological investigation. Results: 1 month after deformity modeling the most severe destructive changes were noticed in muscle fibers adjacent to the peak of deformity on convex side. Tortuosity, swelling, loss of cross striation, nucleus pycnosis with their migration towards the center of fibers, edema of endomysium and perimysium were found. The severity of destructive changes decreased at the distance of the zone of deformity modeling. 3 months after operation the most severe destructive changes in muscle fibers were observed on the convex side of deformity as well. 6 months after deformity modeling on the both convex and concave sides of deformed bone the structure of muscle fibers generally corresponded to the structure of muscle structure of intact animals of appropriate age. The absence of difference in the structure of muscles on convex and concave sides of deformity on this term caused by their restructuring as a reaction to prolonged stress. Conclusions: structural-function peculiarities of the muscle of injured extremity should be taken into consideration while planning the tactics of treatment of long bones posttraumatic treatment

Authors and Affiliations

Kostiantyn Romanenko, Nataliya Ashukina, Dmytro Prozorovsky

Keywords

Related Articles

Morphology of the articular cartilage of the knee joint in rats with extraarticular femoral bone deformity (Морфологія суглобового хряща колінного суглоба щурів за умов позасуглобової деформації стегнової кістки)

Objective: to assess the structural and functional state of the rat knee after modeling posttraumatic extraarticular deformation of the femur. Methods: experiment was performed in 39 white mature (6 months old) male rat...

Stress-strain state of proximal femur after joint arthoroplasty with neck defect conditions at the minor trochanter level with different stem types

In the primary hip arthroplasty, the metaphyseal fixation type stems have proved to be very useful, allowing the stability of the fixation and the diaphyseal section of the femur to remain stable for future revision surg...

Hyaluronic acid drugs in the treatment of joint pathology (literature review) [Препарати гіалуронової кислоти в лікуванні патології опорно-рухової системи (огляд літератури)]

On the base of literature review the possibility of hyaluronic acid application in the treatment of patients with arthritis and diseases of joint adjacent tissues was assessed. hyaluronic acid is important component of j...

State of venous blood flow in the lower extremitiesof patients with fractures of the tibia after plate osteosynthesis

Violation of antegrade blood flow, deep vein thrombosis and pulmo­nary embolism (PE) presents the complex problem in the treatment of trauma patients. The goal: to examine the state of antegrade blood flow in the vessel...

Antimicrobial peculiarities of modified magnesium alloy in vitro [Антибактериальные свойства модифицированного магниевого сплава in vitro]

Infection complications after osteosynthesis happen in 5,3–75,4 % of cases, among them posttraumatic osteomyelitis — in 3–24 % after open and 1–7 % — after surgery of closed fractures. The main infectious agents of surgi...

Download PDF file
  • EP ID EP204449
  • DOI 10.15674/0030-59872016189-94
  • Views 259
  • Downloads 0

How To Cite

Kostiantyn Romanenko, Nataliya Ashukina, Dmytro Prozorovsky (2016). Structural peculiarities of m. quadriceps of femur in experimental rats in the conditions of femur deformity forming. Orthopaedics, Traumatology and Prosthetics, 602(1), 89-94. https://europub.co.uk/articles/-A-204449