Struma Ovarii with Pseudo-Meigs’ Syndrome and Raised Cancer Antigen-125 Levels Masquerading as an Ovarian Carcinoma Case report and literature review

Journal Title: Sultan Qaboos University Medical Journal - Year 2017, Vol 17, Issue 2

Abstract

Te monodermal teratoma struma ovarii is a rare ovarian tumour; however, struma ovarii presenting with pseudo-Meigs’ syndrome and raised cancer antigen (CA)-125 levels is even rarer. In elderly patients, this presentation can potentially lead to a misdiagnosis of a malignant ovarian carcinoma, resulting in unnecessary extensive surgery. We report a 55-year-old female who presented to the Lok Nayak Jai Prakash Narayan Hospital, New Delhi, India, in 2016 with progressive abdominal discomfort, fatigue and abdominal distention. Clinical and radiological features were indicative of a malignant ovarian tumour and ascites. Serum CA-125 levels were elevated at 258 U/mL. A left-sided salpingo-oophorectomy was performed, after which the serum CA-125 levels normalised. Tere was no evidence of recurrence at a six-month follow-up. A frozen section procedure confrmed the diagnosis of a struma ovarii. Tis rare condition should be considered as a differential diagnosis in patients presenting with ovarian masses, ascites and raised CA-125 levels.

Authors and Affiliations

Surekha Yadav| Department of Pathology, Maulana Azad Medical College, New Delhi, India, Reena Tomar| Department of Pathology, Maulana Azad Medical College, New Delhi, India, Nidhi Verma| Department of Pathology, Maulana Azad Medical College, New Delhi, India, Nita Khurana| Department of Pathology, Maulana Azad Medical College, New Delhi, India, Rewa Triathi| Department of Obstetrics & Gynecology, Lok Nayak Jai Prakash Narayan Hospital, New Delhi, Delhi, India

Keywords

Related Articles

The Role of Tofacitinib in the Management of Alopecia Totalis

A37-year-old caucasian female patient was referred to the dermatology unit of the Hosp- ital de Poniente, El Ejido, Spain, in 2017 with alopecia totalis (AT). Te AT had occurred over the past fve months and was classif...

Effect of pegylated interferon on non-responders and relapsers with interferon

Objectives: To assess whether a combination of pegylated interferon (interferon conjugated with polyethylene glycol) and ribavirin can improve the response rate in patients with chronic hepatitis C who either did not re...

Te Learning Organisation and Health Care Education

Te ‘Learning Organisation’ is a concept first described by Peter Senge as an organisation where people continuously learn and enhance their capabilities to create. It consists of five main disciplines: team learning...

Increasing Incidence of Infants with Low Birth Weight in Oman

Tis review article provides an overview of the levels, trends and some possible explanations for the increasing rate of low birth weight (LBW) infants in Oman. LBW data from national health surveys in Oman, and publish...

Download PDF file
  • EP ID EP14779
  • DOI 10.18295/squmj.2016.17.02.017
  • Views 323
  • Downloads 19

How To Cite

Surekha Yadav, Reena Tomar, Nidhi Verma, Nita Khurana, Rewa Triathi (2017). Struma Ovarii with Pseudo-Meigs’ Syndrome and Raised Cancer Antigen-125 Levels Masquerading as an Ovarian Carcinoma Case report and literature review. Sultan Qaboos University Medical Journal, 17(2), 229-233. https://europub.co.uk/articles/-A-14779