Studies on Biological Activities of Some Chiral Cobalt Complexes
Journal Title: PARIPEX-Indian Journal of Research - Year 2015, Vol 4, Issue 12
Abstract
A series of ternary Cobalt(II) Chiral mixed ligand (CML) complexes of the type [Co(MINAP)(aa)∙2H2O] were prepared with sodium salt of p-methylisonitrosoacetophenone as primary ligand, CoSO4.7H2O and chiral amino acid (aa) like L-alanine, L-valine, L-leucine, L-methionine and L-phenylalanine as secondary ligand. The chiral complexes were characterized by elemental analysis and various physicochemical techniques. The antibacterial and antifungal activity of the CML complexes were studied by paper disc diffusion method and Tube dilution method respectively against some pathogenic bacteria like E. coli, S. typhi and S. aureus and some pathogenic fungi C. albicans and A. niger.
Authors and Affiliations
Sunny S. Tarve, Sagar V. Sanap, Raju M. Patil
Keywords
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