"Study Aetiological, Clinical and Metabolic Profile of Hypocalcaemia in Adults"
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
Aims: To study clinical presentations , ascertain etiological factors and associated metabolic parameters in patients with hypocalcaemia Material and Methods: Amongst 236 patients having signs and symptoms of hypocalcaemia were evaluated and 100 patients were enrolled. Result and Discussion: 54% patients were females. Average age in females was 31.74 years. Majority of females (85.18%) were in reproductive age group, six were lactating mothers. Perioral tingling was the commonest clinical presentation in 80% of total patients. Trousseau’s sign is having 80% sensitivity. Sedentary lifestyle, lack of exercise, inadequate sunlight exposure, Burkha, multiparity, inadequate dietary intake of calcium were major contributors for Vitamin D deficiency in Women. Vitamin D insufficiency (<30ng) was found in 74% total patient. 60% patients had ECG changes suggestive of QTc prolongation. Conclusions: Adolescent and young adults are the main age groups who presented with hypocalcaemia and should be worked up for metabolic and genetic diseases. Females have more symptomatic hypocalcaemia than men. Before starting anticonvulsants, supplementation with Vitamin D along with Calcium is must as there is high prevalence of Vitamin D insufficiency and hypocalcaemia. Calcium and Vitamin D supplementation to be considered as a part of standard treatment in cases of CNS tuberculosis where patients are given anticonvulsants and antituberculous drugs together
Authors and Affiliations
Dr. Sanjay Gulhane, Dr. Asmita More
Keywords
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- EP ID EP375782
- DOI 10.9790/0853-1706032535.
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