Study of a regimen of medical abortion for second trimester termination of pregnancy using mifepristone and misoprostol
Journal Title: International Journal of Medical and Health Research - Year 2018, Vol 4, Issue 11
Abstract
Termination of pregnancy between 13-26 weeks constitutes about 10-15 % of all pregnancy terminations but is responsible for two third of all major complications and 50% of all abortion related maternal deaths This study assesses the efficacy of a newer regimen using oral mifepristone 200 mg followed by misoprostol 800 mcg per vaginum 12 hours and 24 hours later in two groups for second trimester pregnancy termination aiming to increase the acceptability and reduce the hospital stay. A total of 100 pregnant women willing for second trimester termination of pregnancy were assigned two groups according to time interval between administration of mifepristone and misoprostol. In group 1, misoprostol 800 mcg was administered per vaginum 12 hours after oral 200 mg mifepristone and in group 2, misoprostol 800 mcg was given after 24 hours of oral 200 mg mifepristone. Successful abortion occurred in 97% women in group1 and 98.8% women in group 2.The acceptability was found to be better in group 1. The proposed newer regimen has comparable efficacy and acceptability as the older regimen and requires lesser hospital stay which is a major concern for the females. At the same time it reduces hospital burden which stands more important for the developing country like India, where health care facilities are already scarce.
Authors and Affiliations
Dr. Snehil, Dr. Abha Sinha
Keywords
Related Articles
- EP ID EP587605
- DOI -
- Views 144
- Downloads 0
Biochemical effects in patients of pediatric nephrotic syndrome related Vitamin D and Calcium metabolism
Minimal Change Disease (MCD) is the leading cause of childhood Nephrotic Syndrome (NS). Therefore in pediatrics nephrotic syndrome, most children beyond the first year of life will be treated with corticosteroids without...
Stem cell therapy: An overview
Stem cell therapy is the new technology used to collect stem cell from bone marrow, peripheral blood and umbilical cord of newborn and introduced into human body for treating various disorders. The newborn disorders like...
Randomised controlled trial of misoprostol alone and mifepristone followed by misoprostol in second trimester medical termination of pregnancy
Introduction: Although the majority of abortions are performed in first trimester, there is still a need for second trimester MTP due to delayed diagnosis of fetal anomalies, financial difficulties in obtaining abortion...
A prospective randomised single blind clinical comparative evaluation of analgesia of nebulised fentanyl (4mcg/kg) with intravenous fentanyl (1mcg/kg) for post operative pain relief in abdominal surgeries
Aim and Objectives: To compare postoperative analgesic efficacy of nebulised fentanyl (4mcg/kg) with intravenous fentanyl (1mcg/kg) in abdominal surgeries by using VAS score and to compare the adverse effects namely Brad...
Original research article: A comparative study of electrocardiographic and echocardiographic findings for the diagnosis of left ventricular hypertrophy in patients presenting with hypertension
Background: Left Ventricular Hypertrophy (LVH) is common in hypertension. The prevalence of LVH increases with the age, severity of hypertension and the duration of hypertension. So presence of LVH indicates a long run o...