STUDY OF ACUTE KIDNEY INJURY IN CHILDREN: ITS AETIOLOGY, CLINICAL PROFILE AND OUTCOME
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 11
Abstract
OBJECTIVES: To determine the incidence, age & sex ratio, analyse the spectrum of Acute Kidney Injury (AKI) in its aetiopathology, complications including mortality, prognostic factors and the role of dialysis in the management. METHODS: This prospective observational study was conducted on serial cases of 30 patients admitted in Paediatrics department from Feb 2012-Aug 2014 (30 months). RESULTS: The incidence of AKI was 0.44%. Children in age group of 0-4 yrs were affected most, predominantly males. Distribution of AKI according to aetiopathogenesis was Acute Tubular Necrosis (ATN) 50%, Haemolytic Uraemic Syndrome (HUS) 19.8%, Glomerulonephritis (GN) 13.2%, Obstructive uropathy 9.9% and Acute on Chronic renal failure (CRF) 6.6%. Dialysis was required in 53.3% of patients. Mortality was 57%. Patients with complications of sepsis, neurological & respiratory problems, hyperkalemia, metabolic acidosis and gastrointestinal bleeding were associated with high mortality. CONCLUSIONS: AKI is a common life threatening condition seen in childhood. Early referral, proper assessment, adequate & timely treatment and prompt institution of dialysis helps in decreasing mortality.
Authors and Affiliations
Garuda Rama
Keywords
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- EP ID EP226416
- DOI 10.18410/jebmh/2015/225
- Views 95
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