Study of Amlodipine Besylate on Acid, Base, Temperature and U.V. Light
Journal Title: International Journal for Research in Applied Science and Engineering Technology (IJRASET) - Year 2016, Vol 4, Issue 2
Abstract
The present paper deals the stability of Amlodipine besylate in acidic and basic pH, heat and under UV light. It also plays many important physiological and metabolic roles and has antioxidant properties. Amlodipine besylate 10mg tablets and by making its dilution 25ug/ml we exposed it to acidic and basic condition, heat and u.v light and noted their absorbance at wavelength 237nm. It is found that Amlodipine absorbance decreases in all the above mentioned stress conditions. It is concluded that stability of Amlodipine besylate decreases in acidic and medium. Stability also decreases in heat and u.v sensitive. The spectrophotometric assay of the degraded solutions of ascorbic acid has revealed that heat degrades ascorbic acid more as compared to UV light and alkaline medium.
Authors and Affiliations
Dr. Saras Tiwari
Keywords
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