Study of an outbreak of respiratory diphtheria in local community,Kakinada
Journal Title: Medpulse International Journal of Microbiology - Year 2019, Vol 10, Issue 3
Abstract
Objectives:1. Isolation, speciation and toxigenicity testing of Corynebacterium diphtheria. 2. To study the epidemiology, clinical features, complications and outcomes in respiratory diphtheria.Materials and Methods: 31 suspected Diphtheria cases admitted in the G G H, Kakinada, were included in the study. Isolates identified by standard methods and toxigenicity by Elek's Gel Precipitation test. Isolates were sent to NICD for confirmation.Results:Out of 31 suspected cases of diphtheria, 8 were smear positive, 10 culture positive, 7 smear plus culture positive. Isolated strains were non toxigenic strains of Corynebacterium diphtheriae.gravis.In smear negative cases, Streptococcus pyogenes6, Staphylococcus aureus(4) were isolated.Clinical features were Fever in 18 cases, dysphagia 7, sore throat 5, Swelling of neck 7,Dyspnoea 3, greyish membrane over tonsils 9, Myocarditis 4, respiratory compromise in 6 cases. Deathoccurred in 10 cases. Nonehad adequate immunization.Unknown history in 27 cases, first dose given in 2, first 3 doses given in 1, 1st booster dose given in 1 case.90% were from lower socio economic groups. First outbreak occurred in Fisherman community, Yetimoga, Kakinada.Survey was done in the area, Source could not be traced .12,405 children below 10 years were immunized Chemoprophylaxis was given to all contacts.Conclusion:Poor immunization and lower socioeconomic status have resulted in an outbreak.Increased immunization coverage, early availability of ADS, early recognition and effective treatment could have reduced the incidence and mortality.
Authors and Affiliations
R Usha Rani, K R L SuryaKirani, A Durga Rani
Keywords
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