Study of Anti-hepatitis B antibody titers in vaccinated Students of Zahedan Dental School in 2012
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 9
Abstract
Hepatitis B is one of the most common infections in the world and one of the major health problems in Iran. Staffs and students of health centers are constantly exposed to infection with hepatitis B virus. The aim of this study is to evaluate the anti-hepatitis B antibody titers in vaccinated students of Zahedan Dental School in 2012. This descriptive and analytical study was conducted by providing questionnaires and serological tests. After completing the questionnaire, the samples from blood of130 eligible students were tested by ELISA test for, HBs Ag and Anti- HBc Anti- HBs testing. The conditions of Anti-HBs titers were divided into three categories: Anti-HBc≤10 (negative), Anti-HBs <100> 10 (good positive), Anti-HBs≥100 (high positive). The relation between titer and some variables was studied. Data were analyzed with Fisher's Chi-square statistical models. In results in this study, 21.5% (n = 28) of students had negative titers (titer less than 10), 19.2% (n = 25) positive titers (with titers ranging from 100 to 10) and 59.2% (n = 77) of students had higher positive titers (titer greater than 100), respectively. Also, none of the variables except history of previous examination Antibody titer, had a significant relation with the antibody. Only 15.4% of the examined people had measured the antibody titers of anti-hepatitis B. in conclusion According to the results of this work, more than 75% of college students had acceptable safety level against hepatitis B. The students with vaccination history whose safety levels were not acceptable had to receive this vaccine again. Keywords: hepatitis B virus, hepatitis B vaccine, antibodies against hepatitis B.
Authors and Affiliations
Somayeh Hosseini Tabatabaei, Forough Amirabadi, Mohammad Naebi, Abdolvahed hossein bor
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