Study of association of hyperthyroidism with intraocular pressure, dry eye and central corneal thickness
Journal Title: Medpulse International Journal of Ophthalmology - Year 2018, Vol 8, Issue 2
Abstract
Purpose: To study the association of Hyperthyroidism on intra ocular pressure, dry eye and central corneal thickness.Materials and method: Study design: Case-control study. In our study we have included 100 hyperthyroid patients and 100 healthy individuals of either sex came to our hospital. All these patients were carefully examined for dry eye, IOP, central corneal thickness. In all cases visual acuity, TBUT, Schirmer’s test, pachymetry, applanation tonometry were performed. Slit lamp examination, fundus examination also done in our OPD. Results were compared with healthy control group.Results: Mean age in hyperthyroid patients was 45±12 years and in healthy individuals mean age was 43±11years. In thyroid patients TBUT was 6.6± 2.3 seconds, Schirmer’s test reading was 10.56±5.1 mm, mean IOP was 16.70±3.20 mmHg, and CCT was 538.9±14.9 µm. In healthy individuals TBUT was 12.9±3.1 seconds, Schirmer’s test reading was 16.95±6.2 mm, mean IOP was 15.98±2.74mmHg, CCT 541.9±13.7 µm. Dry eye was present in 55 smokers and in 19 non smokers in hyperthyroid patients. Conclusion: Our study shows that Schirmer’s test and TBUT were lower in hyperthyroid patients and has a definite association with dry eye. There was no significant change in IOP and CCT in hyperthyroid patients. Smoking was found a risk factor for development of dry eye in hyperthyroidism. As we all know that smoking also aggravates thyroid eye disease so smoking should be avoided to prevent dry eye and its serious consequences in hyperthyroid patients.
Authors and Affiliations
Sanjeev Verma, Sujit Das
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