Study of Biochemical Parameters in Oral Submucous Fibrosis.
Journal Title: International Journal of Medical Science And Advanced Clinical Research (IJMACR) - Year 2019, Vol 2, Issue 1
Abstract
Oral Submucous Fibrosis (OSMF) is a chronic insidious disease with precancerous potential. Since the last decade, there has been constant rise in OSMF in India. This rise in OSMF in India has been attributed to the increased consumption of areca nut. The present study is aimed to estimate serum biochemical parameters i.e. urea, uric acid and creatinine in Early Oral Submucous Fibrosis (EOSMF). The study subjects were divided into 2 groups i.e. Group-I (Early Oral Submucous Fibrosis), Group-II (controls). Group-I includes n=30 patients of clinically diagnosed and histopathologically proven of Early Oral Submucous Fibrosis (EOSMF). They were in the age group of 25-65 years. Group-II (controls) were age and sex-matched, apparently healthy volunteers (n=30) were included in this study. Serum biochemical parameters i.e. urea, uric acid and creatinine were analyzed in all study subjects by Automated Biochemistry Analyzer - ERBA XL 180. Serum urea in Group-I shown mild difference (Mean) when compared with Group-II. There was a decreased (Mean) of serum uric acid observed in Group-I when compared with Group-II. Whereas increased serum creatinine values (Mean) seen in Group-I when compared with Group-II. It is suggested that analysis of biochemical parameters can be helpful in mass screening of the early oral submucous fibrosis.
Authors and Affiliations
B. Vikram
Keywords
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