Study of Bone Mineralization and Renal Function Biochemical Parameters in Preterm and Term Infants
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 6
Abstract
The objective of the presented work was to study and compare different biochemical parameters of bone mineralization and renal function in preterm and term infants. The study included 150 newborn babies admitted in the neonatal unit, of the hospital. The enrolled neonates were divided into study group [further divided into subgroups according to their gestational age (GA) - Group-IA (30-32 weeks of GA &IB (34-36 weeks of GA), 50 neonates in each group] and control group (Group-II also including 50 neonates). Serum calcium, phosphorus, alkaline phosphatase (ALP), creatinine, sodium, and potassium were measured in all the three groups. Serum calcium and phosphorous levels were found to be significantly decreased withP<.001 and p<0.05 respectively, and serum ALP, creatinine, and potassium were found to be significantly increased (P<0.05) in Group-IA as compared Group-II. Serum sodium levels did not show any significant difference. There was no significant difference in calcium and phosphorous levels although they were decreased, whereas serum ALP and creatinine levels were found to be significantly(P<0.05) increased in Group-IA as compared to Group-IB. High serum ALP and creatinine levels and low serum calcium and phosphorus levels were seen inpreterm babies. Group-IB did not show any significant difference when compared to Group-II (control group). It can be concluded that high serum ALP activity and low serum calcium and phosphorus levels are associated with preterm babies. A significant difference in the mean values of the renal function parameters was also obtained, except for serum sodium and potassium levels. Keywords: Gestational Age, Neonates, Bone Mineral Density, Glomerulogenesis.
Authors and Affiliations
Jyoti Bala, Shashi Seth, Veena Singh Ghalaut
Keywords
Related Articles
- EP ID EP374849
- DOI -
- Views 74
- Downloads 0
Correlation of Percutaneous Length of Tibia with Body Height and Estimation of Stature in Living North Indian Males
Stature reconstruction is important as it provides a forensic anthropological estimate of the height of a person in the living state, playing a vital role in identification of individuals from grossly mutilated skeletal...
Study of Salivary IgA in Different Types of Dental Caries
Abstract: Dental caries being a bacterial disease accelerates the immune apparatus of the body and as a result antibodies {salivary and serum} can be found out. The major immunoglobulin in serum, is found only in low lev...
A Study of Spectrum and Prevalence of Anaemia in Patients of Decompensated Chronic Liver Disease in a Rural Tertiary Care Centre in North India
Abstract: Anaemia is a frequently observed manifestation during clinical course of chronic liver disease. This study was planned to assess the prevalence and spectrum of anaemia in decompensated chronic liver disease pat...
Peritubal Local Anaesthetic Infiltration in Postoperative Pain Relief Following Percutaneous Nephrolithotomy - Is It Really Effective? - A Prospective Randomized Controlled Study
Percutaneous nephrolithotomy (PCNL) has become the standard treatment of large renal stones since its advent in 1990s. Post-operative pain is a common problem in patients undergoing PCNL. Several agents have been used to...
Correlation of Pap smear and Colposcopy in Relation to Histopathological Findings in Detection of Premalignant Lesions of Cervix
The objective was to assess the correlation of pap smear and colposcopy in relation to histopathological findings in detection of premalignant lesions of cervix. A total of 200 women with lesions of cervix were recruited...