Study of Changes in Haemetological Parameters in Alcoholism
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 3
Abstract
Alcoholism is a global public health problem with numerous healths, social, legal, psychological and physical consequences. Excessive Alcohol consumption affects virtually every major organ system, and has significant serious consequences on the haematopoietic system affecting blood cells, their progenitors and clotting components. The study was conducted on 28 non alcoholics and 56 alcoholic subjects (28-moderate, 28- severe alcoholics). The results showed maximum alcoholics in the age group of 31-40 years. Mean duration of alcoholism was 11.8 years. In alcoholics Haemoglobin, PCV and platelet count was significantly decreased, MCV was increased. Leucocytosis and leukopenia were seen. Peripheral smear showed increase in macrocytic anaemia. Bone marrow examination showed predominant megaloblastic picture. In conclusion alcoholism has profound effects on haematological and haemostatic parameters in the blood. Duration of alcohol consumption correlated with changes in alcohol parameters. Some of the results in conjunction with the clinical history would also be useful in diagnosing and management of alcoholics. Abstinence can reverse many of alcohols’ effect on haematopoiesis and blood cell function. These simple and affordable investigations help in early detection of complications of alcoholism. Keywords: alcoholism, haematological parameters, mean corpuscular volume
Authors and Affiliations
Dr. Anasuya M, Dr. M. Vijay Kumar, Dr. Gopal Rao S, Dr. C. Ramachandra Bhat, Dr. Ganesh Nayak, Dr. Chirag Gangadhar
Keywords
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