STUDY OF CHANGES IN SERUM ELECTROLYTES AND ITS RISK IN DEVELOPMENT OF SENILE CORTICAL CATARACT
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 27
Abstract
BACKGROUND Cataract is one of the age-related eye disorders due to the opacity in the lens and accounts for 50% of blindness in India. Factors like family history, ageing, alterations in blood electrolytes and diabetes mellitus are involved in formation of senile cataract. Alterations in serum electrolyte levels can induce alterations in the concentration of electrolytes in aqueous humour, which affect the lens metabolism and probably lead to the formation of senile cataract. The aim of the study is to evaluate the effect of the altered levels of serum electrolytes and the risk in development of senile cataract. MATERIALS AND METHODS Our study was a case control study and included 40 senile cataract patients scheduled for cataract surgery in test group and 40 normal individuals of same age group in control group. A 3 mL random venous blood sample was collected from all the subjects who enrolled in our study. Serum electrolytes were measured by ISE method (Ion Selective Electrode) using Sensa Core Electrolyte Analyzer. Data was analysed statistically using GraphPad online software. The mean±SD of electrolytes were calculated and compared by using paired student t-test and p-value was elicited. ‘P’ value of < 0.05 was considered as significant. RESULTS The mean±SD of serum Na+, Cl- in the test group were 143.5±3.6, 102±3.2 respectively. Mean±SD of serum Na+, Cl- in control group were 139±2.4 and 100±2.3 respectively. The test group had significantly higher Na+ level with ‘p’ value of < 0.001 and Cllevel with ‘p’ value of < 0.05 when compared with control group. Mean±SD of serum K+ in test and control group were 3.9±0.4 and 4.1±0.2 respectively. The test group had significantly lower serum K+ with ‘p’ value of < 0.001 when compared with control group. CONCLUSION Our study suggests that diet with high sodium, chloride and low potassium remain significant risk factor in development of senile cataract. Salt restricted diet and consumption of diet rich in potassium should be advised in cataract individuals, so as to maintain normal electrolyte balance in order to prevent further progression of the disease.
Authors and Affiliations
Ch. Chandana Chowdary, Sunanda V. , Jayapal Reddy Y.
Keywords
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- EP ID EP467133
- DOI 10.14260/jemds/2018/700
- Views 81
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