Study of Chronic Complications of Type 2 Diabetes Mellitus in Relation to Vitamin D- in Rural Area of Andhra Pradesh
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 7
Abstract
Introduction: Type 2 diabetes mellitus (T2DM) is one of the most common health problems facing mankind and is a major public health problem. Study aimed to evaluate the relation between 25(OH) vitamin-D levels and chronic vascular complications (micro and macrovascular) in T2DM. Material and methods: A cross-sectional study carried in 2 years. 50 patients with T2DM fulfilling the inclusion and exclusion criteria were included in study. Results: Common age in the study population is 50-60 years with mean age 58.2 ± 8.3 years. Sex ratio of males : females is 1.3:1. In our study prevalence of microvascular complications is 40%. Single microvascular complications (retinopathy or neuropathy or nephropathy) was present in 20% of cases while the combination of all three was present in 12% of cases. At least one Macrovascular complications in our study is 24% of patients. Prevalence’s of individual vascular complications Nephropathy - 28%, Retinopathy - 24%, Neuropathy- 20%, CAD - 20%, CVD - 4%, PVD - 4%. In our study vitamin D deficiency is present in 60% of patients, vitamin D Insufficiency is present in 30% and only 10% of study group had normal vitamin D. Conclusion: Vitamin D deficiency (<20 ng/ml) in type 2 diabetes is associated with any of the microvascular complications, and type 2 diabetics with decreasing vitamin D levels have significantly increasing prevalence of combination of microvascular complications. The vitamin D status of patients with diabetes should be considered during their regular follow-up.
Authors and Affiliations
CH. Manoj Kumar, Manne Gowtam
Keywords
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