Study of Clinical Profile in Patients with H1N1 Influenza in New Civil Hospital Surat, January 2015-September-2015
Journal Title: International Journal Of Research In Medicine - Year 2017, Vol 6, Issue 1
Abstract
BACKGROUND: We describe the clinical profile of patients who were found H1N1 Positive in new civil hospital Surat from 1st January 2015 to 30 September 2015. MATERIAL &METHODS: Retrospective data of 152 patients from New Civil Hospital Surat who were suspected with influenza like illness was collected. They were subjected to throat swab testing for H1N1. Out of them 60 were positive for H1N1 virus with use of real time reverse transcriptase polymerase chain reaction assay. (TAQ MAN real time PCR CDC protocol).Clinical parameters of these 60 patients were analyzed. RESULTS: Out of 152 suspected H1N1 influenza patients, 60 (39.47%) patients were confirmed (positive) for H1N1.Male 33(55%) were affected more than females 27(45%). 23(37.66%) patients had underlying Co-Morbid condition. Fever (98.70%) and cough (100%) were the most common presenting symptom. Total 18 (30%) patients were put on mechanical ventilator. Out of the 60 patients, 20 patients who received oseltamivir within 72 hour of onset of illness, 18 (90%) were cured and 2(10%) expired. 40 Patients who had received oseltamivir after 72 hrs 30(75%) cured and 10(25%) expired . We observed no significant adverse effect of oseltamivir 150 mg twice day dose for 5-7 days. CONCLUSIONS: Maximum patients were between age group of 14-50 year. Fever and cough were most common presenting symptoms. Mechanical ventilatory support had role in reducing mortality. Patients seemed to be benefited more from antiviral therapy if started within 72 hour of onset of symptom. There were no significant adverse effects of Oseltamivir observed in this study. Development of ARDS, requirement of Mechanical ventilation and having co-morbid condition were poor prognostic factors.
Authors and Affiliations
Sweta Gamit, Ashvin Vasava, Ketan Patel, Amit Gamit, Tinkal Patel
Keywords
Related Articles
- EP ID EP437613
- DOI -
- Views 92
- Downloads 0
Study of epidemiology of surgical site infection (SSI) in Public Hospital Setting
BACKGROUND: Surgical site infection (SSI) is defined as infection occurring in the body cavity or deep tissue or subcutaneous space in relation to the surgical wound. Results of infection vary from just inconvenience...
Sickle Cell Disease: Prevalence, Clinical Presentation and Prognosis in Tribes; Current Concepts and Unanswered Question
BACKGROUND: Sickle cell Disease is one of the most common severe monogenic disorder in the world. It is characterized by intermittent Vasoocclusive events and chronic Hemolytic Anemia. Patients clinically present with ea...
Gall Bladder Wall Thickness as a Marker of Portal Hypertension in Patients of Alcoholic Cirrhosis of Liver
BACKGROUND AND OBJECTIVES: One of the major complications of cirrhosis is the occurrence of Portal Hypertension, which can lead to bleeding from Esophageal Varices, Hepatic Encephalopathy, Ascites, Spontanoeus Bacterial...
Thyroid Cytology Evaluation By Bethesda System A Two Year Prospective Study
BACKGROUND: Thyroid lesions are one of the common conditions encountered in clinical practice. It is difficult to clinical evaluation & reach to correct diagnosis. Hence it is essential that a correct diagnosis is made a...
Study of Correlation of Preoperative Clinical Findings, Laboratory Investigations and Sonological Findings on Peroperative Parameters in Gall Stone Disease
BACKGROUND AND OBJECTIVES: Within a short span of merely two decades since its introduction, laparoscopic cholecystectomy (LC) has become widely accepted as the procedure of choice for symptomatic gall bladder disease. T...