STUDY OF CLINICAL, RADIOLOGICAL AND BACTERIOLOGICAL PROFILE OF COMMUNITY ACQUIRED PNEUMONIA AND ASSESSMENT OF SEVERITY IN DIABETIC AND NON-DIABETIC PATIENT
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2017, Vol 5, Issue 2
Abstract
Patients with diabetes are immune compromised. It has been suggested that diabetes mellitus is associated with an increased susceptibility to infections, therisk of using more aggressive therapeutic agents and increased mortality and morbidity; however, current evidence supporting these events in the field of pneumonia is scarce. The aim of the present study is to provide information on clinical and microbiological characteristics and the outcome of pneumonia in patients with diabetes mellitus.This prospective comparative study included 50 patients with proper written consent. The clinical profile, radiological features, and bacteriological profile of CAP in diabetic and non-diabetic patients was studied and compared. The severity was assessed by CURB-65 severity scoring system in CAP in diabetic and non-diabetic patients and outcome was measured. Patient below 18years of age, patient with hospital acquired pneumonia, ventilator associated pneumonia, tuberculosis lung malignancies, opportunistic infections were excluded.In this study total 25 diabetic and 25 non-diabetic patients with CAP were enrolled.Out of the 50 patients studied patients with diabetes were significantly associated with multi-lobar involvement (P=0.045*), prolonged duration of hospital stay (P = <0.001**), more severe at presentation in form of increased CURB-65 score (P = 0.004**) and more ICU admissions. By contrast, there was no significant difference in age, sex, concomitant underlying illness, complications, mortality. In the sub group of patients with diabetes, mortality was associated with multi-lobar infiltrate, concomitant illness, high CURB-65 score.Pulmonary complications were relatively more in diabetics then in non-diabetics. Hospitalised diabetics with CAP required referral to intensive care unit more than that of non-diabetics. Hence diabetic patients with CAP need extra attention.
Authors and Affiliations
Pratik Ranjan, S. K. Jotkar
Keywords
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