Study of congenital malformations and related maternal and foetal factors: Hospital based study

Journal Title: Medpulse International Journal of Pediatrics - Year 2017, Vol 4, Issue 1

Abstract

Background: Congenital malformation represents defects in morphogenesis during early fetal life. According to the World Health Organization (WHO) document of 1972. Aims and Objectives: To Study of Congenital Malformations and related Maternal and Foetal Factors: Hospital Based Study Methodology : This was a cross sectional study carried out at the Paediatric department of the tertiary health care center during one year period from January 2015 to December 2015. All the 5607 newborns at the tertiary health care centre were screened for congenital malformation clinically and history of mothers like Iron Folic acid Consumption, Consanguinity, Maternal age, Fever with Rash, TORCH infection, Exposure to Smoking, Family history were asked. Result: The incidence of malformation was highest in the Age group >31 i.e. 4.26%and above age group followed by 15-20 1.21%; 26-30-0.81%; 21-25-0.43%and overall the incidence was observed to be 1.30%.The majority of the Associated Maternal Factors found were Age more than 31 Yrs. -53.42%; Inadequate IFA Supplementation -34.24%; H/o Fever with Rash -26.02%;H/o TORCH infection -20.54% H/o Exposure to Smoking -17.80%;Family history -16.43%;Consanguineous marriage -13.69%. The fetal factors associated with the Malformations were Male gender i.e. 63.01% followed by Low birth weight 61.64% ; Twins -20.54%; Birth order >4 -19.17%. Conclusion: In our study we have observed Maternal Factors associated were Age more than 31 Yrs. Inadequate IFA Supplementation; H/o Fever with Rash ;H/o TORCH infection-;H/o Exposure to Smoking; Family history ;Consanguineous marriage; The fetal factors associated with the Malformations were Male gender i.e. 63.01% followed by Low birth weight; Twins ; Birth order >4.

Authors and Affiliations

Bhushan A Miraje, Amar V Naik, Uday A Miraje, Meghana G Kamble, Snehal A Harne

Keywords

Related Articles

A study of the different treatment strategies and outcome of babies with meconium stained amniotic fluid

Background: Meconium aspiration syndrome (MAS) is defined as respiratory distress in an infant born through meconium-stained amniotic fluid (MSAF) with characteristic radiological changes and whose symptoms cannot be oth...

Reticulocytosis and direct coombs test as markers of haemolysis in neonatal hyperbilirubinemia requiring phototherapy

Background: Neonatal hyperbilirubinemia is seen in 60% full-term neonates in first week of life. Among these8-11 % require phototherapy. Causes of hyperbilirubinemia can be immune or non-immune causes. Reticulocytosis an...

Clinicosocial profile of Beta-Thalassaemia major patients attending at tertiary health care centre Nanded, Maharashtra

Background: Thalassaemia is one of the most prevalent autosomal recessive diseases in the world. According to WHO, 4.5% of the world population is carrier of haemoglobinopathies, out of which around 40 million are in Sou...

Study of hematological and coagulation profile of term neonates born to mothers with PIH as compared to term neonates born to normotensive mothers

Objectives: To study the changes in Hematological and Coagulation profile of newborns born to mothers with hypertensive disorders of pregnancy and in neonates born to normotensive mothers. Methods: A prospective study to...

Role of serum zinc level in simple febrile seizures: A hospital based study from rural area of Maharashtra

Introduction: Febrile Convulsion is the most common type of seizure in children between 5 months to 6 years of age. Low levels of serum zinc suggestive of increased incidence of simple febrile seizure. Aim: The aim of th...

Download PDF file
  • EP ID EP260259
  • DOI -
  • Views 299
  • Downloads 0

How To Cite

Bhushan A Miraje, Amar V Naik, Uday A Miraje, Meghana G Kamble, Snehal A Harne (2017). Study of congenital malformations and related maternal and foetal factors: Hospital based study. Medpulse International Journal of Pediatrics, 4(1), 10-12. https://europub.co.uk/articles/-A-260259