Study of correlation between obstructive sleep apnea and obstructive airway disease
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 2
Abstract
Background: The association between OSA and obstructive airway disease (OAD), including both asthma and chronic obstructive pulmonary disease (COPD) has been studied previously. A high prevalence of OSA has been reported in asthma cases. Sleep related symptoms do also occur in patients of COPD. This study was undertaken to find the correlation between obstructive sleep apnea and obstructive airway disease, with the help of spirometry and polysomnography. Material and Methods: The present study was conducted in sleep laboratory on 114 patients of COPD, bronchial asthma and obstructive sleep apnea. Baseline spirometry was done with computerized Medgraphics Spirometer and divided as per post bronchodilator FEV1reversibility as, those with asthma and with COPD. Asthma was diagnosed on the basis of Global Initiative for Asthma guidelines (GINA) and COPD based on Global Initiative for obstructive lung Disease guidelines. The apnea-hypopnea index was used to quantitate the severity of obstructive sleep apnea. Results: Amongst patients with COPD and asthma, majority had moderate to severe COPD. Amongst COPD and asthma patients, 22 (28.20%) and 12 (33.33%) patients were found to have obstructive sleep apnea. In patients having severe OSA, (10out 12 patients) had more severe grade of bronchial asthma with FEV1 <80%. This suggest that presence of asthma may lead to worsening of sleep apnea and vice versa. Discussion: In patients having overlap syndrome had more severe (50.59) hypercapnia, and nocturnal desaturation (mean 85.88%). Patients having moderate COPD had severe OSA. Patients having severe asthma had severe OSA with correlation coefficient of -0.676.
Authors and Affiliations
Gajanan Vaijnath Halkanche, D G Mhaisekar
Keywords
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