Study of cytodiagnosis of discharge per vaginum with specific reference to human papilloma virus and herpes simplex virus at tertiary care center, Indore
Journal Title: International Journal of Medical Science and Public Health - Year 2017, Vol 6, Issue 7
Abstract
Background: Cervical cancers are the second most frequent type of female cancer. Human papillomavirus (HPV) infection is the most important risk factor for cervical cancer. Objective: The aim is to detect cytomorphological changes of HPV and herpes simplex virus (HSV) to early diagnose cervical cancer to prevent it at early stage. Materials and Methods: The study includes total 1542 patients presenting with the complaints of vaginal discharge and/or associated symptoms. Samples were taken, and prepared smear was stained with papanicolaou (PAP) stain and reporting was done according to The Bethesda system - 2014. The study was prospective study and statically analyzed. Results: Totally, 1542 PAP smears were analyzed. Out of which, normal smears 364 (23.61%), inadequate smears 58 (3.76%), inflammatory smear 1093 cases (70.88%), and epithelial cell abnormality comprises 27 cases (1.75%). Out of 27 cases, atypical squamous cells of undetermined significance was the most common epithelial cell abnormality (63%). Cytomorphological features of HPV infection are seen in 2 cases of low-grade squamous intraepithelial lesion, 2 cases of high-grade squamous intraepithelial lesion, and 5 cases of the malignant lesion while inflammatory smear suspicious of HSV comprises 2 cases (0.13%). Conclusions: The incidence of cervical cancer can be decreased if PAP smear screening is done at an early age and in the females having high-risk factors.
Authors and Affiliations
Khushboo Likhar, Meena Mittal, C V Kulkarni, Monica Verma, Rakesh Mehar, Vipin Todase
Keywords
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- EP ID EP317569
- DOI 10.5455/ijmsph.2017.0306524032017
- Views 71
- Downloads 0
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