Study of Dexmedetomidine as intramuscular premedication in outpatient cataract surgery: A placebo – controlled study
Journal Title: International Archives of Integrated Medicine - Year 2016, Vol 3, Issue 2
Abstract
Aim: To evaluate the effects of Dexmedetomidine to reduce the intra ocular pressure and sedation in day care cataract surgeries. Materials and methods: This study was conducted in 50 patients of either sex, belonging to 40 – 60 years of age, ASA grade I and II admitted for cataract surgeries. Patients were randomized into two groups of 25 each. Group D received 1 mcg/mg of Dexmedetomidine as IM route, Group P received placebo as IM and intra ocular pressure changes, hemodynamic parameters, sedation levels and SPO2, anxiolysis and pain were monitored. Results: There was a statistically significant difference in group D before and after premedication in terms of intra ocular pressure reduction. This was not seen in placebo group. Systolic blood pressure, diastolic blood pressure and heart rate in the study was a statistically difference in group D before and after premedication. There was no statistically significant difference in group P before and after premedication. There was a statistically significant difference (P<0.05) between the group D and group P in terms of sedation. Oxygen saturation observed in group D and group P at intervals of 0, 10, 20, 30, 40, 50, 60 min showed no statistical significance (P>0.05). There was a statistically significant difference (P<0.05) between the group D and group P in terms of pain relief and anxiety after premedication. Conclusion: Results suggested that Dexmedetomidine produces sedation and a reduction of intra-ocular pressure with minimal hemodynamic side effects when given intramuscularly as premedication before cataract surgery under regional anesthesia.
Authors and Affiliations
D. Srinivasa Naik, K. Ravi Kumar, Surendra Babu, R. Pandu Naik
Keywords
Related Articles
- EP ID EP417808
- DOI -
- Views 86
- Downloads 0
Diagnostic correlation of palpable breast masses by cytology and histopathology: A prospective study
Introduction: Fine needle aspiration cytology (FNAC) has revolutionized the approach to diagnosis and management of breast and various other lesions. Its accuracy in many situations avoids any unnecessary surgical proced...
Sebaceous carcinoma of eyelid – Understanding its unique cytomorphology and role of aspiration cytology
Introduction: Sebaceous carcinoma is a very rare malignant tumor primarily found in the area of the eyelid. We have reported here a case of sebaceous carcinoma of the eyelid with neck node metastasis diagnosed on fine ne...
Role of CT imaging to evaluate solitary pulmonary nodule with extrapulmonary neoplasms
Background: A solitary pulmonary nodule is defined as a discrete, well - marginated, rounded opacity less than or equal to 3 cm in diameter that is completely surrounded by lung parenchyma, does not touch...
A comprehensive study on effect of recombinant human epidermal growth factor gel in diabetic foot ulcer
Background: Ulcer healing in the diabetic patients is challenging due to a prolonged inflammatory response, extracellular matrix degradation irregularities, and increased bacteria presence. Recombinant human epidermal gr...
Prospective Study on Road Traffic Accident Cases in Sub-urban Region of Chennai, Tamil Nadu State
The present study consists of 100 road traffic injury cases admitted in our tertiary health care centre. In the present study, males victims (84 cases, 84%) outnumbered the females victims (16 cases, 16%) with an approxi...