STUDY OF DYNAMICS OF CHANGES IN THE LEVEL OF SOME BLOOD CITOKINS IN PATIENTS WITH VARIOUS TYPES OF COMPLICATED PANCREATIC PSEUDOСYST
Journal Title: Science Review - Year 2018, Vol 4, Issue 3
Abstract
The study of TGF-β1, IL-6, IL-10, IL-18, IL-8 in patients with complicated pseudocysts has been performed. The obtained data, testify to one of the leading roles of TGF-β1 in the development of intra-and perilobular fibrosis, regardless of the trigger mechanism of pancreatitis and its complications. It has been established that the definition of circulating TGF-β1 may reflect the different stages of pancreatitis and the severity of the complications that develop at different times from the moment of the disease. Il-10, a powerful TGF-b1, controls the regeneration phase, reduces fibrosis and atrophy, and IL-18 stimulates apoptosis. Thus, the data obtained by us confirm the hypothesis that the activation of pro-inflammatory cytokine IL-18 and anti-inflammatory cytokine IL-10 can form a link between the risk factors for the development of complications in patients with different types of pancreatic pseudocyst.
Authors and Affiliations
I. A. Kryvoruchko, N. Нoncharova, S. M. Teslenko, A. V. Syvozhelizov, A. G. Drozdova, P. V. Svirepo, O. I. Prokhorov, I. M. Timofeev
Keywords
Related Articles
- EP ID EP354600
- DOI -
- Views 116
- Downloads 0
АНАЛІЗ НЕБЕЗПЕК, ЩО ВИНИКАЮТЬ ПРИ ПЕРЕВЕЗЕННІ НЕБЕЗПЕЧНИХ ВАНТАЖІВ
Maritime transport is of paramount importance for the implementation of foreign trade (international and intercontinental) links. It provides more than 4/5 of all international traffic. One of the activities of Maritime...
РОЖДЕНИЕ ОРКЕСТРА УЗБЕКСКИХ НАРОДНЫХ ИНСТРУМЕНТОВ
In Uzbekistan, for a long time, there was monophonic (unison) music. And they always played by ear. At present, there are two large directions of instrumental performance on folk instruments. The first is a traditional i...
ПОРІВНЯЛЬНИЙ АНАЛІЗ РЕФОРМИ ДЕРЖАВНОГО УПРАВЛІННЯ В УКРАЇНІ ТА СЛОВАЧЧИНІ
The main directions of the reform of the system of public administration in the Slovak Republic and Ukraine are considered. The historical aspects of the establishment of local self-government in Slovakia and Ukraine are...
СТАН ТА ЧИННИКИ ПОШИРЕНОСТІ ТЮТЮНОКУРІННЯ СЕРЕД СТУДЕНТОК ПЕДАГОГІЧНОГО УНІВЕРСИТЕТУ
The paper highlights the results of the survey of students at the pedagogical university so that to identify the outspread, intensity, causes and age of initiation (commencement) of tobacco smoking. The survey included 6...
МНОЖЕСТВА ЕВКЛИДОВЫХ КОМБИНАТОРНЫХ КОНФИГУРАЦИЙ: ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ
In this paper, a class of the Euclidean combinatorial configurations sets (e-configurations sets) is discussed. Their connection with combinatorial configurations sets and the Euclidean combinatorial sets is established....