Study of effect of Mitomycin-C on long term results in Endonasal Dacryocystorhinostomy
Journal Title: Medpulse International Journal of ENT - Year 2017, Vol 1, Issue 3
Abstract
Aim and Objective: To evaluate the efficacy of topical application of Mitomycin-C for prevention of stomal stenosis in Endonasal Dacryocystorhinostomy (DCR). Materials and Methods: 45 patients undergoing endonasal DCR for chronic dacryocystitis were studied prospectively. The follow up period was 6 months. Dacryocystogram was done preoperatively in every patient. Group allocation was done randomly. Group A subjected to topical application of Mitomycin-C after surgery while group B was control group. Post operatively sac syringing and endoscopic evaluation of stomal patency was done for every patient at regular intervals. Results: 92% cases of Mitomycin-C group and 85% cases of the control group had long term successful results. This result is statistically not significant (p > 0.05). Conclusion: Intraoperative Mitomycin-C application is useful to improve long term results though the study is not significant statistically.
Authors and Affiliations
Hitendra Joshi, Ashfaque Ansari, Rajendra Bohra, Reena Vare
Keywords
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