Study of Efficacy and Safety of Ormeloxifene in Management of Abnormal Uterine Bleeding
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 2
Abstract
Introduction: Abnormal uterine bleeding (AUB) is one of the most common conditions for which women consult their gynaecologists. Study was done to evaluate the efficacy and adverse reactions of ormeloxifene in patients with abnormal uterine bleeding. Material and Methods: This was single centred, open label, 6 months prospective study. 53 patients with complaints of abnormal uterine bleeding having PBAC Score more than 100 were enrolled in study. Ormeloxifene 60mg twice a week was given for 3 months followed by 60 mg once a week for next 3 months. At follow ups, patients were assessed for Endometrial thickness by USG, Haemoglobin level, PBAC score and adverse effects of drug therapy. Results: A total 53 patients with the mean age of 32.91±6.82 were enrolled, in which 45 patients completed the follow up. There was statistically significant decrease in endometrial thickness, haemoglobin level and PBAC score. Conclusion: Thus Ormeloxifene, a non-steroidal, nonhormonal agent, with its convenient dose schedule provides effective and favourable medical treatment.
Authors and Affiliations
Tajinder Kaur, Rakesh C. Chaurasia, Amrita Chaurasia
Keywords
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