Study of Efficacy of Intradermal Injection of Tranexamic Acid and 50% Glycolic Acid Peeling in Treatment of Melasma
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 5, Issue 11
Abstract
Background: Melasma is one of the most common causes of facial hyperpigmentation which causes cosmetic disfigurement and leads to psychological problems. Although various treatments are available for melasma, it remains a difficult condition to treat. Aim of the Work: The aim of the study was to evaluate and compare the efficacy of intradermal injection of tranexamic acid and glycolic acid peeling in the treatment of melasma. Patients and Methods: A total of 112 patients with melasma were divided into two groups: Group A; 56 patients were treated with an intradermal injection of tranexamic acid and Group B 56 patients were treated with glycolic acid peeling 50%. Clinical assessment (according to the modified Melasma area and severity index) was performed for all patients. Results: There was a statistically significant difference between the studied groups as regards the response to different therapeutic modalities with the best results in Group A than Group B. There was the statistically significant difference between A and B, Group A showed a better response than Group B. Conclusion: This signifies that tranexamic acid is more effective than commonly used 50% glycolic acid peel. Furthermore, the recurrence of melasma was found to be less in tranexamic acid as compared to glycolic acid 50%.
Authors and Affiliations
K U Kaushik, Shivangi Sachan, Ali Mohammad
Keywords
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